Interactor 1: INHBA (P08476)
Inhibin beta A chain (Activin beta-A chain) (Erythroid differentiation protein) (EDF)
Gene: INHBA

Interactor 2: ACV1B (P36896)
Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)
Gene: ACVR1B

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 9202237, 22267736, 7890768, 9605406
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~TGF_beta
Common GO terms GO:0001942 - hair follicle development
GO:0007399 - nervous system development
GO:0010628 - positive regulation of gene expression
GO:0030308 - negative regulation of cell growth
GO:0032924 - activin receptor signaling pathway
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 426
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024