Interactor 1: ODPA (P08559)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Gene: PDHA1

Interactor 2: SIR3 (Q9NTG7)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)
Gene: SIRT3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 24486017, 34079125
Identification Methods enzymatic study, affinity chromatography technology, proximity labelling technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 390
Hs

1 399
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024