HitPredict

Interactor 1: PLEK (P08567)
Pleckstrin (Platelet 47 kDa protein) (p47)
Gene: PLEK

Interactor 2: WDR75 (Q8IWA0)
WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog)
Gene: WDR75

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.706

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEP~WD40, PH~WD40
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 350 Hs			1 830
+	Hs
		1016298 RHG24_HUMAN (226-347): 1.42e-26: 112: 29.23		TBL3_HUMAN (1-491): 1e-71: 253: 11.49
+	Hs
		787153 RHG25_HUMAN (229-348): 1.44e-26: 112: 28.35		TBL3_HUMAN (1-491): 1e-71: 253: 11.49
+	Hs
		1153371 PKHA7_HUMAN (111-349): 5.5e-25: 108: 16.22		TBL1R_HUMAN (329-669): 7.31e-53: 194: 10.14
+	Hs
		1240465 PKHA5_HUMAN (2-248): 5.65e-27: 114: 14.07		POC1A_HUMAN (1-181): 2.15e-35: 141: 17.39
+	Hs
		903302 PKHA7_HUMAN (111-349): 5.5e-25: 108: 16.22		WDR5_HUMAN (477-696): 2.27e-34: 136: 15.25
+	Hs
		254103 RHG24_HUMAN (226-347): 1.42e-26: 112: 29.23		WDR1_HUMAN (435-740): 2.78e-22: 104: 9.18
+	Hs
		254096 PKHA7_HUMAN (111-349): 5.5e-25: 108: 16.22		WDR1_HUMAN (435-740): 2.78e-22: 104: 9.18