Protein: RT106
Histone chaperone RTT106 (Regulator of Ty1 transposition protein 106)

Gene: RT106, RTT106
Organism: Saccharomyces cerevisiae S288C
Interactions: 88
UniProt ID: P40161

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003690 - double-stranded DNA binding
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

820432

H3
Histone H3

16

0

Small-scale

0.937

High

382131

H4
Histone H4

10

0

Small-scale

0.927

High

820417

RT106
Histone chaperone RTT106

3

0

Small-scale

0.831

High

381119

H2B1
Histone H2B.1

2

1

High-throughput

0.737

High

381526

H2B2
Histone H2B.2

2

1

High-throughput

0.737

High

739651

SPT16
FACT complex subunit SPT16

2

0

Small-scale

0.716

High

419754

H2A2
Histone H2A.2

2

0

High-throughput

0.699

High

820439

CAF1B
Chromatin assembly factor 1 subunit B

4

1

Small-scale

0.672

High

737673

HIR2
Protein HIR2

3

2

Small-scale

0.660

High

803827

BCD1
Box C/D snoRNA protein 1

3

0

Small-scale

0.645

High

820421

RSC8
Chromatin structure-remodeling complex protein RSC8

2

1

Small-scale

0.619

High

820418

ATAD2
ATPase histone chaperone YTA7

3

0

Small-scale

0.606

High

737635

HIR1
Protein HIR1

2

3

Small-scale

0.594

High

820442

POB3
FACT complex subunit POB3

1

0

Small-scale

0.586

High

736654

ASF1
Histone chaperone ASF1

2

0

Small-scale

0.577

High

820455

H2AZ
Histone H2A.Z

1

1

High-throughput

0.575

High

794184

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

2

High-throughput

0.571

High

820420

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

1

Small-scale

0.561

High

820453

CAF1A
Chromatin assembly factor 1 subunit A

2

0

Small-scale

0.560

High

550661

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.554

High

567724

MSI1
Histone-binding protein MSI1

2

0

Small-scale

0.547

High

586464

PCNA
Proliferating cell nuclear antigen

2

0

Small-scale

0.547

High

820435

HPC2
Histone promoter control protein 2

2

0

Small-scale

0.547

High

694211

BUD14
Bud site selection protein 14

1

0

High-throughput

0.518

High

440942

CDC7
Cell division control protein 7

1

1

Small-scale

0.501

High

814203

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.494

High

416549

HXKB
Hexokinase-2

1

0

High-throughput

0.493

High

364565

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

440850

KIN28
Serine/threonine-protein kinase KIN28

1

0

High-throughput

0.480

High

673705

KCC4
Probable serine/threonine-protein kinase KCC4

1

0

High-throughput

0.480

High

748851

SWE1
Mitosis inhibitor protein kinase SWE1

1

0

High-throughput

0.480

High

809045

POP2
Poly(A) ribonuclease POP2

1

0

Small-scale

0.480

High

444854

SIR3
Regulatory protein SIR3

1

1

Small-scale

0.479

High

743031

SWI3
SWI/SNF complex subunit SWI3

1

1

High-throughput

0.479

High

402020

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

448971

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

614828

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

0

Small-scale

0.458

High

617798

SNF6
Transcription regulatory protein SNF6

1

0

Small-scale

0.458

High

688749

RFA2
Replication factor A protein 2

1

0

Small-scale

0.458

High

707240

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

745760

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

750047

PDR3
Transcription factor PDR3

1

0

Small-scale

0.458

High

820429

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

820447

ELG1
Telomere length regulation protein ELG1

1

0

Small-scale

0.458

High

820449

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

820450

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

820451

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

820454

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

524108

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526827

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

734428

BTAF1
TATA-binding protein-associated factor MOT1

1

4

High-throughput

0.445

High

741674

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

743096

STH1
Nuclear protein STH1/NPS1

1

3

High-throughput

0.445

High

744306

CHD1
Chromo domain-containing protein 1

1

1

High-throughput

0.445

High

745588

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

1

High-throughput

0.445

High

803985

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.445

High

820426

INO80
Chromatin-remodeling ATPase INO80

1

2

High-throughput

0.445

High

820438

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.445

High

820443

ARP9
Actin-like protein ARP9

1

1

High-throughput

0.445

High

820444

RSC3
Chromatin structure-remodeling complex protein RSC3

1

1

High-throughput

0.445

High

820446

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

3

High-throughput

0.445

High

820452

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.445

High

545067

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

561481

TBP
TATA-box-binding protein

1

0

High-throughput

0.426

High

678323

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.426

High

713268

MCM5
Minichromosome maintenance protein 5

1

0

High-throughput

0.426

High

793931

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.426

High

805511

ORC6
Origin recognition complex subunit 6

1

0

High-throughput

0.426

High

820424

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.426

High

820425

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.426

High

820427

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.426

High

820428

H1
Histone H1

1

0

High-throughput

0.426

High

820430

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.426

High

820431

ACT
Actin

1

0

High-throughput

0.426

High

820434

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

820436

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

0

High-throughput

0.426

High

820437

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

820441

DPB4
DNA polymerase epsilon subunit D

1

0

High-throughput

0.426

High

820445

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

792408

BOI1
BEM1-interacting protein 1

1

0

High-throughput

0.282

High

820423

BBC1
Myosin tail region-interacting protein MTI1

1

0

High-throughput

0.282

High

820433

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.282

High

820440

MYO5
Myosin-5

1

0

High-throughput

0.282

High

820419

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.249

Low

810954

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

820422

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low

820448

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025