HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: BTNL2 (Q9UIR0)
Butyrophilin-like protein 2 (BTL-II)
Gene: BTNL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Sema~V-set, TIG~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1390 Hs			1 482
+	Hs
		441555 MET_HUMAN (1-1390): 0: 1283: 100.00		LRIG1_HUMAN (30-358): 3.85e-16: 83.6: 17.73
+	Hs
		441498 MET_HUMAN (1-1390): 0: 1283: 100.00		PTK7_HUMAN (31-459): 1.74e-15: 81.3: 18.83
+	Mm
		101572 F8VQL0_MOUSE (1-1381): 0: 1244: 89.50		NCAM1_MOUSE (354-480): 3.93e-11: 67.8: 12.59
+	Hs
		981930 RON_HUMAN (23-1390): 0: 934: 32.70		BTNL2_HUMAN (1-482): 2.36e-96: 300: 100.00
+	Hs
		981901 RON_HUMAN (23-1390): 0: 934: 32.70		TITIN_HUMAN (368-479): 1.48e-09: 62.8: 12.39
+	Hs
		850509 PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82		BTNL2_HUMAN (1-482): 2.36e-96: 300: 100.00
+	Hs
		530151 EPHA3_HUMAN (584-1379): 1.09e-179: 561: 18.13		NCAM1_HUMAN (354-480): 1.78e-11: 68.6: 13.33
+	Hs
		165267 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		BTNL2_HUMAN (1-482): 2.36e-96: 300: 100.00
+	Hs
		411521 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		BTNL2_HUMAN (1-482): 2.36e-96: 300: 100.00
+	Hs
		1355881 PLXA1_HUMAN (461-1020): 8.14e-54: 209: 20.36		BTNL2_HUMAN (1-482): 2.36e-96: 300: 100.00
+	Hs
		713822 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		CD276_HUMAN (1-476): 3.14e-79: 258: 21.91
+	Hs
		165213 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		BTNL8_HUMAN (27-288): 5.76e-66: 222: 31.46
+	Hs
		165214 PLXB2_HUMAN (365-1012): 1.26e-58: 225: 16.57		BTNL3_HUMAN (231-468): 1.03e-58: 202: 33.19
+	Hs
		255218 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		ICOSL_HUMAN (252-444): 8.99e-26: 108: 20.10
+	Hs
		987242 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		PTK7_HUMAN (31-459): 1.74e-15: 81.3: 18.83
+	Hs
		530168 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		NCAM1_HUMAN (354-480): 1.78e-11: 68.6: 13.33
+	Hs
		713796 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		PTK7_HUMAN (31-459): 1.74e-15: 81.3: 18.83
+	Hs
		435631 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		PTK7_HUMAN (31-459): 1.74e-15: 81.3: 18.83
+	Hs
		411375 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		PTK7_HUMAN (31-459): 1.74e-15: 81.3: 18.83
+	Hs
		530154 RYK_HUMAN (1078-1334): 2.54e-59: 218: 39.47		NCAM1_HUMAN (354-480): 1.78e-11: 68.6: 13.33