HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 29802200
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 437 Hs			1 2157
+	Hs
		516406 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		820908 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		820889 TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		235754 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		516546 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		235895 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		516595 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05
+	Hs
		965152 PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86		ANK2_HUMAN (12-1866): 6e-46: 186: 11.09
+	Hs
		516749 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		441944 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		442598 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		1288650 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		516609 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		1357831 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83
+	Hs
		235805 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		ANK2_HUMAN (12-1866): 6e-46: 186: 11.09
+	Hs
		516766 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		442632 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		1031405 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60
+	Hs
		62539 RFOX3_HUMAN (24-230): 3.58e-37: 139: 19.05		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		236025 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78