Protein: TM108
Protein TMA108 (EC 3.4.11.-) (108 kDa translation machinery-associated protein)

Gene: TM108, TMA108
Organism: Saccharomyces cerevisiae S288C
Interactions: 227
UniProt ID: P40462

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005854 - nascent polypeptide-associated complex
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

824897

TM108
Protein TMA108

2

7

High-throughput

0.743

High

452579

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

2

1

High-throughput

0.601

High

809329

STM1
Suppressor protein STM1

2

0

High-throughput

0.576

High

392842

HSP82
ATP-dependent molecular chaperone HSP82

2

5

High-throughput

0.571

High

676058

MAS5
Mitochondrial protein import protein MAS5

2

5

High-throughput

0.571

High

818928

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.571

High

524156

HSP71
Heat shock protein SSA1

2

9

High-throughput

0.552

High

670795

SIS1
Protein SIS1

2

3

High-throughput

0.533

High

679763

CDC48
Cell division control protein 48

2

3

High-throughput

0.533

High

454451

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

824954

YTM1
Ribosome biogenesis protein YTM1

1

2

High-throughput

0.489

High

149801

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

416130

SYTC
Threonine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

417114

VDAC1
Non-selective voltage-gated ion channel 1

1

2

High-throughput

0.479

High

427309

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.479

High

430865

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

High-throughput

0.479

High

433224

RL17A
Large ribosomal subunit protein uL22A

1

2

High-throughput

0.479

High

438307

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.479

High

438712

SC160
Protein SCP160

1

2

High-throughput

0.479

High

444543

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.479

High

450598

FAS1
Fatty acid synthase subunit beta

1

2

High-throughput

0.479

High

453632

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.479

High

510549

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.479

High

518309

IF4A
ATP-dependent RNA helicase eIF4A

1

3

High-throughput

0.479

High

557602

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

2

High-throughput

0.479

High

579519

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

585629

STI1
Heat shock protein STI1

1

4

High-throughput

0.479

High

592293

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.479

High

598874

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

2

High-throughput

0.479

High

623869

MYO2
Myosin-2

1

1

High-throughput

0.479

High

645742

HSP74
Heat shock protein SSA4

1

9

High-throughput

0.479

High

689496

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

721627

RENT1
ATP-dependent helicase NAM7

1

2

High-throughput

0.479

High

726221

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

5

High-throughput

0.479

High

727083

HS104
Heat shock protein 104

1

5

High-throughput

0.479

High

736490

MDHP
Malate dehydrogenase, peroxisomal

1

2

High-throughput

0.479

High

738099

MYO4
Myosin-4

1

1

High-throughput

0.479

High

739387

ZUO1
Zuotin

1

4

High-throughput

0.479

High

747893

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

790205

GLYC
Serine hydroxymethyltransferase, cytosolic

1

2

High-throughput

0.479

High

790257

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

2

High-throughput

0.479

High

802088

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

3

High-throughput

0.479

High

804211

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.479

High

811616

YCFI
Metal resistance protein YCF1

1

1

High-throughput

0.479

High

812051

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

813939

RBG1
Ribosome-interacting GTPase 1

1

1

High-throughput

0.479

High

815137

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

815814

BEM2
GTPase-activating protein BEM2/IPL2

1

2

High-throughput

0.479

High

817258

ARB1
ABC transporter ATP-binding protein ARB1

1

5

High-throughput

0.479

High

817873

IMB4
Importin subunit beta-4

1

3

High-throughput

0.479

High

824901

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

824904

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

824908

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.479

High

824909

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.479

High

824913

ASNS1
Asparagine synthetase [glutamine-hydrolyzing] 1

1

3

High-throughput

0.479

High

824914

ASNS2
Asparagine synthetase [glutamine-hydrolyzing] 2

1

2

High-throughput

0.479

High

824916

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.479

High

824918

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

3

High-throughput

0.479

High

824919

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.479

High

824921

HFM1
ATP-dependent DNA helicase MER3

1

3

Small-scale

0.479

High

824924

ASCC3
RQC trigger complex helicase SLH1

1

2

High-throughput

0.479

High

824929

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.479

High

824936

SYH1
SMY2 homolog 2

1

1

High-throughput

0.479

High

824938

RLI1
Translation initiation factor RLI1

1

3

High-throughput

0.479

High

824940

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.479

High

824943

RRB1
Ribosome assembly protein RRB1

1

2

High-throughput

0.479

High

824952

NEW1
[NU+] prion formation protein 1

1

7

High-throughput

0.479

High

824957

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

2

High-throughput

0.479

High

824960

NOT5
General negative regulator of transcription subunit 5

1

1

High-throughput

0.479

High

154324

MBF1
Multiprotein-bridging factor 1

1

0

High-throughput

0.458

High

368451

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

383315

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

439354

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

452512

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.458

High

453959

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.458

High

471408

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.458

High

511432

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.458

High

512090

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

514669

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

518046

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.458

High

553624

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.458

High

558754

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

569797

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

570044

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

572600

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

613590

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.458

High

632902

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

0

High-throughput

0.458

High

645439

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

657095

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

664304

SSD1
Protein SSD1

1

0

High-throughput

0.458

High

666479

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

674663

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

678688

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.458

High

678971

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.458

High

684747

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

709803

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

738389

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.458

High

761118

NOT4
General negative regulator of transcription subunit 4

1

0

High-throughput

0.458

High

795768

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

0

High-throughput

0.458

High

796586

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.458

High

805599

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

806465

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

813987

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

816653

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

824899

FKS2
1,3-beta-glucan synthase component GSC2

1

0

High-throughput

0.458

High

824912

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

824915

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

824923

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

824925

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

824926

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.458

High

824930

NOP3
Serine/arginine

1

0

High-throughput

0.458

High

824931

MAP1
Methionine aminopeptidase 1

1

0

High-throughput

0.458

High

824932

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

824934

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

0

High-throughput

0.458

High

824941

NAB6
RNA-binding protein NAB6

1

0

High-throughput

0.458

High

824945

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

824947

HEL2
E3 ubiquitin-protein ligase HEL2

1

0

High-throughput

0.458

High

824948

MRD1
Multiple RNA-binding domain-containing protein 1

1

0

High-throughput

0.458

High

824949

YL419
Putative ATP-dependent RNA helicase YLR419W

1

0

High-throughput

0.458

High

824950

PBP4
Protein PBP4

1

0

High-throughput

0.458

High

824951

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.458

High

824953

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

526861

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

545124

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

154178

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.437

High

367047

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.437

High

367388

CISY1
Citrate synthase, mitochondrial

1

2

High-throughput

0.437

High

368689

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

383138

RLA4
Large ribosomal subunit protein P2B

1

2

High-throughput

0.437

High

409739

RL24A
Large ribosomal subunit protein eL24A

1

2

High-throughput

0.437

High

427705

RLA2
Large ribosomal subunit protein P2A

1

2

High-throughput

0.437

High

432855

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.437

High

433031

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.437

High

434168

RL36A
Large ribosomal subunit protein eL36A

1

1

High-throughput

0.437

High

435580

RS9B
Small ribosomal subunit protein uS4B

1

1

High-throughput

0.437

High

438446

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.437

High

441948

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

482032

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.437

High

502736

RS21A
Small ribosomal subunit protein eS21A

1

1

High-throughput

0.437

High

503800

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.437

High

504249

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

504533

RL31B
Large ribosomal subunit protein eL31B

1

2

High-throughput

0.437

High

531768

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.437

High

597477

EF3A
Elongation factor 3A

1

7

High-throughput

0.437

High

601063

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.437

High

603488

VATA
V-type proton ATPase catalytic subunit A

1

7

High-throughput

0.437

High

609064

SKI3
Superkiller protein 3

1

2

High-throughput

0.437

High

618594

FAS2
Fatty acid synthase subunit alpha

1

2

High-throughput

0.437

High

626763

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.437

High

642145

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.437

High

663682

RL24B
Large ribosomal subunit protein eL24B

1

2

High-throughput

0.437

High

689054

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.437

High

689226

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.437

High

712588

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.437

High

737614

HS150
Cell wall mannoprotein HSP150

1

1

High-throughput

0.437

High

737734

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

2

High-throughput

0.437

High

747406

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

751087

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

1

High-throughput

0.437

High

755110

GCN1
eIF-2-alpha kinase activator GCN1

1

6

High-throughput

0.437

High

808512

TEM1
Protein TEM1

1

6

High-throughput

0.437

High

811990

RS14B
Small ribosomal subunit protein uS11B

1

1

High-throughput

0.437

High

815301

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

High-throughput

0.437

High

816843

NUG1
Nuclear GTP-binding protein NUG1

1

1

High-throughput

0.437

High

820897

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.437

High

821014

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.437

High

824898

PHB1
Prohibitin-1

1

4

High-throughput

0.437

High

824902

VTC2
Vacuolar transporter chaperone complex subunit 2

1

2

High-throughput

0.437

High

824903

RSSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.437

High

824905

RL17B
Large ribosomal subunit protein uL22B

1

2

High-throughput

0.437

High

824906

MTR4
ATP-dependent RNA helicase DOB1

1

3

High-throughput

0.437

High

824907

VTC4
Vacuolar transporter chaperone complex subunit 4

1

2

High-throughput

0.437

High

824910

TCB2
Tricalbin-2

1

2

High-throughput

0.437

High

824917

PHB2
Prohibitin-2

1

4

High-throughput

0.437

High

824920

RL9B
Large ribosomal subunit protein uL6B

1

1

High-throughput

0.437

High

824922

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

824927

EF3B
Elongation factor 3B

1

7

High-throughput

0.437

High

824928

ACAC
Acetyl-CoA carboxylase

1

3

High-throughput

0.437

High

824933

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.437

High

824935

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

2

High-throughput

0.437

High

824937

PIR1
Cell wall mannoprotein PIR1

1

1

High-throughput

0.437

High

824939

TCB3
Tricalbin-3

1

2

High-throughput

0.437

High

824942

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

High-throughput

0.437

High

824944

VBA4
Vacuolar basic amino acid transporter 4

1

1

High-throughput

0.437

High

824958

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.437

High

824959

TCB1
Tricalbin-1

1

2

High-throughput

0.437

High

824962

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.437

High

824963

RS21B
Small ribosomal subunit protein eS21B

1

1

High-throughput

0.437

High

811101

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.407

High

367982

ENO2
Enolase 2

1

0

High-throughput

0.249

Low

402027

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

408580

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.249

Low

410172

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433679

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

434385

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.249

Low

434589

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.249

Low

455101

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503082

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

503394

RL11A
Large ribosomal subunit protein uL5A

1

0

High-throughput

0.249

Low

511209

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

511806

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.249

Low

513045

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

513373

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.249

Low

513507

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.249

Low

513697

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

514009

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.249

Low

514150

RS16B
Small ribosomal subunit protein uS9B

1

0

High-throughput

0.249

Low

514298

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

515111

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

515266

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.249

Low

528829

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.249

Low

555096

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

673107

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.249

Low

676937

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.249

Low

740067

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

High-throughput

0.249

Low

746037

YME2
Mitochondrial escape protein 2

1

0

High-throughput

0.249

Low

753408

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

781206

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.249

Low

795025

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

812367

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

817490

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

0

High-throughput

0.249

Low

824900

RL33B
Large ribosomal subunit protein eL33B

1

0

High-throughput

0.249

Low

824911

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.249

Low

824946

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.249

Low

824955

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

824956

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.249

Low

824961

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025