HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29802200, 29298432
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck GO:0071011 - precatalytic spliceosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 953
+	Hs
		516580 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1201589 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1201808 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		91478 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		E7ERS3_HUMAN (1-953): 2.86e-78: 277: 97.54
+	Hs
		235937 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		516749 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		516609 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54
+	At
		188091 RU17_ARATH (5-381): 5.96e-39: 147: 39.95		U2A2A_ARATH (368-468): 1.02e-26: 118: 37.62
+	Hs
		442324 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15
+	Hs
		442598 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		965152 PABP3_HUMAN (4-361): 3.46e-50: 181: 11.86		ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63
+	Hs
		442299 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1288650 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		1357831 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		1031405 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54
+	Ce
		107192 SIG7_CAEEL (30-257): 1.69e-32: 129: 24.12		RPB1_CAEEL (601-926): 3.58e-10: 66.2: 17.38
+	Hs
		703409 CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		235805 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63