Protein: PDCD1
Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279)

Gene: PDCD1
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q15116

Gene Ontology (top 5):
GO:0001783 - B cell apoptotic process
GO:0002250 - adaptive immune response
GO:0002644 - negative regulation of tolerance induction
GO:0002903 - negative regulation of B cell apoptotic process
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1067951

PD1L1
Programmed cell death 1 ligand 1

9

4

Small-scale

0.976

High

1067939

PD1L2
Programmed cell death 1 ligand 2

3

4

Small-scale

0.884

High

738347

BMR1A
Bone morphogenetic protein receptor type-1A

2

0

High-throughput

0.770

High

1067921

WDFY3
WD repeat and FYVE domain-containing protein 3

2

0

High-throughput

0.770

High

1067924

DGLB
Diacylglycerol lipase-beta

2

0

High-throughput

0.770

High

557331

GDC
Solute carrier family 25 member 16

2

4

High-throughput

0.726

High

1067934

MFRN2
Mitoferrin-2

2

4

High-throughput

0.726

High

1067942

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

2

4

High-throughput

0.726

High

1067959

ORNT1
Mitochondrial ornithine transporter 1

2

4

High-throughput

0.726

High

309900

UCP5
Brain mitochondrial carrier protein 1

1

3

High-throughput

0.691

High

518362

ADT3
ADP/ATP translocase 3

1

3

High-throughput

0.691

High

1067925

GLT11
Polypeptide N-acetylgalactosaminyltransferase 11

2

0

High-throughput

0.679

High

1067926

MCU
Calcium uniporter protein, mitochondrial

2

0

High-throughput

0.679

High

1067935

S2546
Mitochondrial outer membrane protein SLC25A46

2

0

High-throughput

0.679

High

1067956

NOCT
Nocturnin

2

0

High-throughput

0.679

High

1055120

HLTF
Helicase-like transcription factor

1

0

High-throughput

0.656

High

1067944

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.656

High

1067945

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.656

High

706897

CD80
T-lymphocyte activation antigen CD80

1

3

Small-scale

0.647

High

1067913

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

4

High-throughput

0.618

High

1067923

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.618

High

1067915

RHDF2
Inactive rhomboid protein 2

2

0

High-throughput

0.602

High

1067928

SPPL3
Signal peptide peptidase-like 3

2

0

High-throughput

0.602

High

1067953

S53A1
Solute carrier family 53 member 1

2

0

High-throughput

0.602

High

985958

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

1

Small-scale

0.593

High

252831

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

0

High-throughput

0.578

High

796405

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

1

High-throughput

0.574

High

1067954

GCP4
Gamma-tubulin complex component 4

2

1

High-throughput

0.574

High

1067932

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.517

High

616812

JAK1
Tyrosine-protein kinase JAK1

1

0

High-throughput

0.513

High

901925

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

912913

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.513

High

1057880

DIP2A
Disco-interacting protein 2 homolog A

1

0

High-throughput

0.513

High

1067911

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

0

High-throughput

0.513

High

1067916

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

Small-scale

0.501

High

1067947

RN167
E3 ubiquitin-protein ligase RNF167

1

2

Small-scale

0.501

High

1067936

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.489

High

1067938

ARL5B
ADP-ribosylation factor-like protein 5B

1

1

High-throughput

0.489

High

925872

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.480

High

1067929

RN128
E3 ubiquitin-protein ligase RNF128

1

2

Small-scale

0.457

High

665893

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

1

Small-scale

0.407

High

64430

RTL8C
Retrotransposon Gag-like protein 8C

2

0

High-throughput

0.328

High

686173

GLPK
Glycerol kinase

2

0

High-throughput

0.328

High

1002093

ABD18
Protein ABHD18

2

0

High-throughput

0.328

High

1067918

T126B
Complex I assembly factor TMEM126B, mitochondrial

2

0

High-throughput

0.328

High

1067919

DEN6A
Protein DENND6A

2

0

High-throughput

0.328

High

1067920

PLPL6
Patatin-like phospholipase domain-containing protein 6

2

0

High-throughput

0.328

High

1067930

CHPT1
Cholinephosphotransferase 1

2

0

High-throughput

0.328

High

1067931

FAM3C
Protein FAM3C

2

0

High-throughput

0.328

High

1067933

POP5
Ribonuclease P/MRP protein subunit POP5

2

0

High-throughput

0.328

High

1067937

INT4
Integrator complex subunit 4

2

0

High-throughput

0.328

High

1067941

RCAF1
GEL complex subunit OPTI

2

0

High-throughput

0.328

High

1067943

SFXN3
Sideroflexin-3

2

0

High-throughput

0.328

High

1067949

INT7
Integrator complex subunit 7

2

0

High-throughput

0.328

High

1067955

XPO7
Exportin-7

2

0

High-throughput

0.328

High

181864

SOCS1
Suppressor of cytokine signaling 1

2

0

Small-scale

0.313

High

49139

TM223
Transmembrane protein 223

1

0

High-throughput

0.279

Low

503215

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.279

Low

840373

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.279

Low

1067912

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

1067914

CC033
Protein C3orf33

1

0

High-throughput

0.279

Low

1067917

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.279

Low

1067922

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.279

Low

1067927

NAV1
Neuron navigator 1

1

0

High-throughput

0.279

Low

1067940

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.279

Low

1067946

EMRE
Essential MCU regulator, mitochondrial

1

0

High-throughput

0.279

Low

1067948

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.279

Low

1067950

RTEL1
Regulator of telomere elongation helicase 1

1

0

High-throughput

0.279

Low

1067952

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.279

Low

1067958

T184B
Transmembrane protein 184B

1

0

High-throughput

0.279

Low

1067960

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

0

High-throughput

0.279

Low

1067957

AGO1
Protein argonaute-1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024