HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11850407
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 605
+	Hs
		516754 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1031501 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		236140 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		516733 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1031492 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1327900 CSTFT_HUMAN (84-177): 2.89e-20: 95.3: 30.85		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		236126 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1259857 PPIL4_HUMAN (63-356): 2.16e-35: 138: 17.17		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		235994 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		516438 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		209382 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		196943 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Dm
		1129076 SET1_DROME (53-387): 1.25e-41: 160: 20.59		WDS_DROME (457-605): 2.3e-37: 144: 25.16
+	Hs
		903196 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		235781 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33