HitPredict

Interactor 1: RAS1 (P08646)
Ras-like protein 1 (Dras1) (EC 3.6.5.2) (Dmras85D)
Gene: Ras85D

Interactor 2: P91634 (P91634)
PI-3 kinase (Phosphatidylinositol 3-kinase 92E, isoform A) (Phosphatidylinositol 3-kinase 92E, isoform B) (Phosphatidylinositol 3-kinase 92E, isoform C (EC 2.7.1.-, EC 2.7.1.137, EC 2.7.1.153, EC 2.7.1.154)) (Phosphoinositide 3-kinase, Dp110) (SD05105p)
Gene: Pi3K92E

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 17041587, 15710747
Identification Methods two hybrid, affinity chromatography technology, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~Ras, PI3K_rbd~Ras
Common GO terms GO:0002168 - instar larval development
GO:0005886 - plasma membrane
GO:0007552 - metamorphosis
GO:0008361 - regulation of cell size
GO:0009267 - cellular response to starvation
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Dm

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Last updated: 15 Jul 2024