HitPredict

Interactor 1: RAS1 (P08646)
Ras-like protein 1 (Dras1) (EC 3.6.5.2) (Dmras85D)
Gene: Ras85D

Interactor 2: RGS (Q9VCX1)
Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco)
Gene: loco

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PDZ~Ras, RBD~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 189 Dm			1 1541
+	Dm
		442972 RAP1_DROME (1-163): 2.09e-63: 195: 57.32		RGS_DROME (1-1541): 0: 1824: 100.00
+	Dm
		443011 RAS1_DROME (1-189): 6.58e-77: 229: 100.00		Q9VCX2_DROME (711-1541): 0: 973: 99.64
+	Dm
		442973 RAP1_DROME (1-163): 2.09e-63: 195: 57.32		Q9VCX2_DROME (711-1541): 0: 973: 99.64
+	Hs
		207504 RASH_HUMAN (1-181): 2.05e-92: 269: 81.22		RGS14_HUMAN (813-1293): 2.69e-166: 514: 30.33
+	Hs
		158596 RASH_HUMAN (1-181): 2.05e-92: 269: 81.22		RGS12_HUMAN (70-509): 1.11e-148: 494: 32.91
+	Rn
		139845 RASH_RAT (1-181): 2.05e-92: 269: 81.22		RGS12_RAT (70-516): 2.41e-148: 492: 31.34
+	Mm
		956619 RAB35_MOUSE (4-186): 2.5e-83: 246: 31.96		RGS14_MOUSE (813-1293): 6.55e-165: 510: 30.88
+	Rn
		139848 RASN_RAT (1-170): 3.42e-90: 263: 83.53		RGS12_RAT (70-516): 2.41e-148: 492: 31.34
+	Mm
		867148 RAB2A_MOUSE (4-179): 5.82e-75: 225: 30.90		RGS14_MOUSE (813-1293): 6.55e-165: 510: 30.88
+	Mm
		918978 RAB1A_MOUSE (4-187): 2.22e-74: 224: 31.28		RGS14_MOUSE (813-1293): 6.55e-165: 510: 30.88
+	Hs
		207516 RAP1A_HUMAN (1-165): 5.07e-62: 192: 55.69		RGS14_HUMAN (813-1293): 2.69e-166: 514: 30.33
+	Hs
		207624 RB11A_HUMAN (4-178): 4.33e-73: 221: 33.90		AKA10_HUMAN (596-978): 6.7e-84: 291: 15.92
+	Hs
		782023 RAP1B_HUMAN (1-189): 6.47e-74: 222: 50.26		RGS2_HUMAN (755-947): 5.99e-61: 209: 26.29