HitPredict

Interactor 1: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Interactor 2: NSD3 (Q9BZ95)
Histone-lysine N-methyltransferase NSD3 (EC 2.1.1.370) (EC 2.1.1.371) (Nuclear SET domain-containing protein 3) (Protein whistle) (WHSC1-like 1 isoform 9 with methyltransferase activity to lysine) (Wolf-Hirschhorn syndrome candidate 1-like protein 1) (WHSC1-like protein 1)
Gene: NSD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 1437
+	Mm
		444974 RPB1_MOUSE (375-496): 7.84e-09: 60.7: 19.67		NSD2_MOUSE (140-1416): 0: 825: 45.08
+	Hs
		443233 NFIC_HUMAN (1-508): 1.61e-162: 472: 100.00		EHMT2_HUMAN (1029-1281): 2.28e-60: 229: 22.84
+	Hs
		443252 NFIC_HUMAN (1-508): 1.61e-162: 472: 100.00		EHMT1_HUMAN (995-1301): 1.89e-59: 227: 20.54
+	Hs
		1060355 NFIX_HUMAN (2-507): 2.17e-156: 456: 56.73		EHMT2_HUMAN (1029-1281): 2.28e-60: 229: 22.84
+	Hs
		1060369 NFIX_HUMAN (2-507): 2.17e-156: 456: 56.73		EHMT1_HUMAN (995-1301): 1.89e-59: 227: 20.54
+	Hs
		1018269 NFIA_HUMAN (2-508): 1.69e-133: 398: 59.20		EHMT1_HUMAN (995-1301): 1.89e-59: 227: 20.54
+	Hs
		975253 NFIX_HUMAN (2-507): 2.17e-156: 456: 56.73		KMT2A_HUMAN (1131-1285): 7.1e-40: 164: 30.13
+	Hs
		135163 NFIB_HUMAN (1-423): 2.4e-128: 381: 63.47		EHMT1_HUMAN (995-1301): 1.89e-59: 227: 20.54
+	Hs
		1060330 NFIX_HUMAN (2-507): 2.17e-156: 456: 56.73		KMT2C_HUMAN (1278-1411): 2.31e-13: 77.9: 15.75
+	Hs
		1060388 NFIX_HUMAN (2-507): 2.17e-156: 456: 56.73		KMT2B_HUMAN (1323-1421): 9.58e-09: 62.5: 19.83
+	Hs
		135133 NFIB_HUMAN (1-423): 2.4e-128: 381: 63.47		KMT2C_HUMAN (1278-1411): 2.31e-13: 77.9: 15.75
+	Hs
		1296427 RERE_HUMAN (185-495): 5.48e-30: 126: 13.87		EHMT2_HUMAN (1029-1281): 2.28e-60: 229: 22.84
+	Hs
		625023 RPB1_HUMAN (374-496): 2.39e-09: 62.2: 20.33		SETD2_HUMAN (1004-1320): 1.62e-59: 228: 32.18
+	Hs
		975338 RERE_HUMAN (185-495): 5.48e-30: 126: 13.87		KMT2A_HUMAN (1131-1285): 7.1e-40: 164: 30.13
+	Mm
		444963 RPB1_MOUSE (375-496): 7.84e-09: 60.7: 19.67		EHMT1_MOUSE (995-1301): 7.13e-59: 225: 20.83
+	Hs
		624909 RPB1_HUMAN (374-496): 2.39e-09: 62.2: 20.33		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		624870 RPB1_HUMAN (374-496): 2.39e-09: 62.2: 20.33		KMT2A_HUMAN (1131-1285): 7.1e-40: 164: 30.13
+	Hs
		975285 KMT2C_HUMAN (177-499): 7.42e-09: 60.7: 11.98		KMT2A_HUMAN (1131-1285): 7.1e-40: 164: 30.13
+	Hs
		1350537 RERE_HUMAN (185-495): 5.48e-30: 126: 13.87		KMT2B_HUMAN (1323-1421): 9.58e-09: 62.5: 19.83
+	Hs
		625001 RPB1_HUMAN (374-496): 2.39e-09: 62.2: 20.33		NSD1_HUMAN (91-724): 2.53e-28: 126: 15.30