HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	10887173, 36931259, 15161933, 20618440
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0019904 - protein domain specific binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 245
+	Hs
		409047 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		409044 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		569067 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		409008 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		409014 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		569050 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Mm
		372933 GFAP_MOUSE (80-465): 2.2e-129: 383: 61.14		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Hs
		443445 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		443346 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		443356 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		409042 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		409055 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		409015 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Rn
		677657 VIME_RAT (14-466): 1.07e-109: 334: 97.35		1433B_RAT (1-242): 2e-128: 364: 86.78
+	Hs
		646928 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		443441 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		443469 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		443357 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Hs
		904613 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		684061 AINX_HUMAN (82-422): 6.14e-97: 302: 54.91		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97