HitPredict

Interactor 1: IL3 (P08700)
Interleukin-3 (IL-3) (Hematopoietic growth factor) (Mast cell growth factor) (MCGF) (Multipotential colony-stimulating factor) (P-cell-stimulating factor)
Gene: IL3

Interactor 2: IL3RA (P26951)
Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123)
Gene: IL3RA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.884

Property	Details
Experiments	8649415, 7957082, 29374162
Identification Methods	pull down, coimmunoprecipitation, saturation binding, molecular sieving, x-ray crystallography
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IL3~IL3Ra_N, IL3~IL6Ra-bind
Common GO terms	GO:0038156 - interleukin-3-mediated signaling pathway
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 378
+	Hs
		444046 IL3_HUMAN (1-152): 2.33e-102: 291: 100.00		IL3RB_HUMAN (108-295): 4.67e-12: 69.5: 12.39