HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: K1C17 (Q04695)
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
Gene: KRT17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29859926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0030855 - epithelial cell differentiation GO:0045109 - intermediate filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 432
+	Hs
		444298 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K1C19_HUMAN (77-394): 1.39e-146: 424: 73.59
+	Hs
		444309 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K1C15_HUMAN (83-426): 2.02e-141: 413: 68.66
+	Hs
		444368 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT81_HUMAN (21-397): 2.65e-91: 287: 26.46
+	Hs
		444351 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT83_HUMAN (21-402): 2.82e-91: 286: 26.63
+	Hs
		444352 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT85_HUMAN (3-397): 7.18e-91: 285: 27.27
+	Hs
		213926 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT86_HUMAN (21-397): 6.62e-90: 282: 26.46
+	Hs
		444413 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C73_HUMAN (4-398): 3.6e-88: 279: 25.68
+	Hs
		318769 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C75_HUMAN (9-406): 3.84e-84: 269: 25.75
+	Hs
		444390 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C79_HUMAN (9-406): 3.64e-81: 261: 22.89
+	Hs
		444380 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C71_HUMAN (27-398): 3.87e-77: 250: 23.00
+	Hs
		444371 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C72_HUMAN (35-398): 2.83e-76: 248: 24.59
+	Hs
		380437 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6B_HUMAN (50-414): 2.7e-73: 241: 23.43
+	Hs
		444336 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6C_HUMAN (50-398): 4.63e-73: 241: 23.93
+	Hs
		444305 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C5_HUMAN (50-398): 1.34e-72: 240: 25.07
+	Hs
		359453 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6A_HUMAN (50-414): 3.75e-72: 238: 23.71
+	Hs
		318831 K1C26_HUMAN (5-395): 7.25e-144: 418: 49.13		K2C75_HUMAN (9-406): 3.84e-84: 269: 25.75
+	Mm
		1322195 K1C17_MOUSE (27-393): 1.22e-147: 427: 67.58		K2C7_MOUSE (5-397): 4.25e-71: 233: 25.89
+	Hs
		380496 K1C26_HUMAN (5-395): 7.25e-144: 418: 49.13		K2C6B_HUMAN (50-414): 2.7e-73: 241: 23.43
+	Hs
		359511 K1C26_HUMAN (5-395): 7.25e-144: 418: 49.13		K2C6A_HUMAN (50-414): 3.75e-72: 238: 23.71
+	Hs
		444491 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT82_HUMAN (135-429): 3.24e-10: 64: 14.87