HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: BFSP1 (Q12934)
Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H) [Cleaved into: Filensin C-terminal fragment; Filensin N-terminal fragment]
Gene: BFSP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005882 - intermediate filament GO:0005886 - plasma membrane GO:0045109 - intermediate filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 665
+	Hs
		408980 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C8_HUMAN (36-346): 2.06e-110: 343: 19.24
+	Hs
		444309 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K1C15_HUMAN (39-320): 1.26e-88: 285: 16.56
+	Hs
		444354 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K1C17_HUMAN (33-326): 2.21e-88: 284: 16.31
+	Hs
		444298 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K1C19_HUMAN (31-317): 6.61e-86: 276: 14.78
+	Hs
		444351 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT83_HUMAN (14-334): 7.29e-71: 240: 15.63
+	Hs
		444368 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT81_HUMAN (14-334): 5.39e-70: 237: 15.34
+	Hs
		213926 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT86_HUMAN (14-334): 2.53e-68: 232: 15.06
+	Hs
		444352 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT85_HUMAN (14-334): 1.39e-65: 226: 15.34
+	Hs
		444491 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT82_HUMAN (15-334): 2.16e-63: 220: 16.81
+	Hs
		318769 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C75_HUMAN (12-323): 4.11e-60: 212: 14.49
+	Hs
		444390 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C79_HUMAN (12-333): 1.56e-58: 207: 15.97
+	Hs
		444380 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C71_HUMAN (12-326): 1.4e-54: 196: 15.52
+	Hs
		444371 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C72_HUMAN (14-323): 1.22e-51: 188: 15.45
+	Hs
		380437 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6B_HUMAN (12-323): 1.62e-50: 186: 16.23
+	Hs
		444305 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C5_HUMAN (12-323): 5.09e-50: 185: 15.36
+	Hs
		444336 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6C_HUMAN (12-323): 2.53e-50: 185: 16.23
+	Hs
		359453 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6A_HUMAN (12-323): 1.13e-48: 181: 16.52
+	Hs
		318831 K1C26_HUMAN (5-395): 7.25e-144: 418: 49.13		K2C75_HUMAN (12-323): 4.11e-60: 212: 14.49
+	Hs
		359511 K1C26_HUMAN (5-395): 7.25e-144: 418: 49.13		K2C6A_HUMAN (12-323): 1.13e-48: 181: 16.52
+	Hs
		444413 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C73_HUMAN (148-488): 6.22e-09: 61.2: 10.47