HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: K2C73 (Q86Y46)
Keratin, type II cytoskeletal 73 (Cytokeratin-73) (CK-73) (Keratin-73) (K73) (Type II inner root sheath-specific keratin-K6irs3) (Type-II keratin Kb36)
Gene: KRT73

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 540
+	Hs
		444407 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C1B_HUMAN (43-463): 2.23e-167: 488: 61.22
+	Hs
		380538 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C1_HUMAN (97-463): 2.77e-157: 464: 66.76
+	Hs
		408980 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C8_HUMAN (104-467): 2.16e-139: 413: 61.26
+	Hs
		444424 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C78_HUMAN (62-461): 1.18e-134: 402: 59.50
+	Hs
		444380 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C71_HUMAN (1-540): 1.75e-96: 304: 79.44
+	Hs
		444352 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT85_HUMAN (3-447): 6.42e-94: 297: 49.56
+	Hs
		318769 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C75_HUMAN (1-457): 3.54e-93: 296: 57.38
+	Hs
		444368 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT81_HUMAN (3-447): 1.91e-92: 293: 48.76
+	Hs
		444351 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT83_HUMAN (3-495): 2.62e-92: 292: 44.63
+	Hs
		213926 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT86_HUMAN (3-504): 1.09e-91: 291: 44.62
+	Hs
		444390 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C79_HUMAN (18-517): 1.54e-86: 279: 55.03
+	Hs
		444371 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C72_HUMAN (1-540): 1.07e-85: 276: 68.82
+	Hs
		444405 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C74_HUMAN (1-540): 1.33e-80: 263: 69.76
+	Hs
		380437 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6B_HUMAN (2-469): 3.05e-79: 260: 57.03
+	Hs
		444336 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6C_HUMAN (2-469): 6.18e-79: 260: 56.63
+	Hs
		444305 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C5_HUMAN (1-448): 2.08e-78: 259: 57.65
+	Hs
		359453 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C6A_HUMAN (2-469): 1.45e-75: 251: 57.03
+	Hs
		444310 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K2C4_HUMAN (12-464): 1.37e-72: 242: 63.26
+	Hs
		444353 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		K22O_HUMAN (1-460): 1.03e-66: 229: 57.53
+	Hs
		444491 K1C19_HUMAN (1-400): 3.13e-157: 450: 100.00		KRT82_HUMAN (178-499): 2.94e-11: 68: 11.38