HitPredict

Interactor 1: H3 (P08898)
Histone H3
Gene: his-2

Interactor 2: H4 (P62784)
Histone H4
Gene: his-1

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26952210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Histone
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 136 Ce			1 103
+	Hs
		917093 H31_HUMAN (1-136): 1.95e-62: 189: 97.79		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Mm
		918236 H31_MOUSE (1-136): 1.95e-62: 189: 97.79		H4_MOUSE (1-103): 3.12e-48: 150: 99.03
+	Xl
		917056 Q92133_XENLA (1-136): 2.15e-61: 186: 96.32		H4_XENLA (1-103): 3.12e-48: 150: 99.03
+	Hs
		917112 H33_HUMAN (1-136): 1.36e-61: 186: 94.12		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Hs
		917352 H31T_HUMAN (1-136): 1.89e-61: 186: 94.85		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Mm
		918240 H33_MOUSE (1-136): 1.36e-61: 186: 94.12		H4_MOUSE (1-103): 3.12e-48: 150: 99.03
+	Xl
		917054 H32_XENLA (1-136): 3.97e-61: 185: 97.06		H4_XENLA (1-103): 3.12e-48: 150: 99.03
+	Hs
		917483 H32_HUMAN (1-136): 3.97e-61: 185: 97.06		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Mm
		918239 H32_MOUSE (1-136): 3.97e-61: 185: 97.06		H4_MOUSE (1-103): 3.12e-48: 150: 99.03
+	Hs
		917448 H3C_HUMAN (1-136): 2.79e-58: 178: 91.18		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Sp
		448920 H31_SCHPO (1-136): 1.4e-59: 181: 89.71		H4_SCHPO (18-103): 1.08e-41: 133: 88.37
+	Hs
		1174638 H32_HUMAN (1-136): 3.97e-61: 185: 97.06		H4G_HUMAN (1-98): 2.86e-38: 125: 83.67
+	Sc
		356652 H3_YEAST (1-136): 4.9e-56: 172: 86.77		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Ce
		711990 HCP3L_CAEEL (11-131): 4.93e-45: 149: 44.36		H4_CAEEL (1-103): 7.75e-49: 152: 100.00
+	Hs
		828186 CENPA_HUMAN (9-133): 2.95e-44: 143: 48.49		H4_HUMAN (1-103): 3.12e-48: 150: 99.03
+	Kl
		1150023 CENPA_KLULA (14-134): 2.66e-44: 144: 54.84		Q6CMU6_KLULA (18-103): 2.24e-41: 133: 90.70
+	Sc
		356401 CENPA_YEAST (18-134): 4.95e-42: 140: 55.00		H4_YEAST (18-103): 1.48e-40: 131: 89.54