HitPredict

Interactor 1: ROS1 (P08922)
Proto-oncogene tyrosine-protein kinase ROS (EC 2.7.10.1) (Proto-oncogene c-Ros) (Proto-oncogene c-Ros-1) (Receptor tyrosine kinase c-ros oncogene 1) (c-Ros receptor tyrosine kinase)
Gene: ROS1

Interactor 2: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2347 Hs			1 314
+	Hs
		665514 EPHA8_HUMAN (1383-2242): 1.9e-173: 562: 18.61		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		411470 INSR_HUMAN (1424-2308): 7.33e-167: 555: 23.13		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		435731 IGF1R_HUMAN (1442-2307): 3.63e-161: 538: 23.25		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		987276 TYRO3_HUMAN (1514-2218): 1.53e-145: 479: 23.85		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		1294127 ALK_HUMAN (1858-2311): 4.31e-84: 309: 38.96		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		434262 RET_HUMAN (1940-2216): 6.4e-64: 241: 42.76		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00