HitPredict

Interactor 1: MYO1 (P08964)
Myosin-1 (Type II myosin)
Gene: MYO1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.909

The method score is based on:

Property Details
Experiments 9201989, 11805826, 26921299, 16429126
Identification Methods biochemical, biophysical, tandem affinity purification, pull down, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Myosin_head
Common GO terms GO:0000142 - cellular bud neck contractile ring
GO:0005524 - ATP binding
GO:1902404 - mitotic actomyosin contractile ring contraction
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1928
Sc

1 375
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Dm
+ Dm
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024