HitPredict

Interactor 1: H2AV (P08985)
Histone H2A.v (H2A.F/Z) (H2A.Z)
Gene: His2Av

Interactor 2: H4 (P84040)
Histone H4
Gene: His4

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	27956707
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CENP-T_C~Histone, CENP-T_C~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005694 - chromosome GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 141 Dm			1 103
+	Hs
		555395 H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		391638 H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		469987 H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		470324 H2A1_HUMAN (5-132): 2.4e-59: 181: 60.47		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		594838 H2A1D_HUMAN (5-132): 2.65e-59: 181: 61.24		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917438 H2A2A_HUMAN (5-132): 1.71e-59: 181: 61.24		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917496 H2A3_HUMAN (5-132): 2.18e-59: 181: 61.24		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917699 H2A1C_HUMAN (5-132): 1.83e-59: 181: 60.47		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917817 H2A1J_HUMAN (5-130): 2.43e-59: 181: 60.63		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917485 H2AV_HUMAN (1-122): 6.81e-59: 180: 98.36		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917757 H2A1H_HUMAN (5-130): 6.24e-59: 180: 60.63		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917544 H2A2B_HUMAN (5-132): 8.46e-59: 179: 59.69		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917354 H2A2C_HUMAN (5-131): 5.82e-58: 177: 60.94		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		470137 H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36		H4G_HUMAN (1-98): 1.39e-38: 126: 83.67
+	Sc
		356810 H2AZ_YEAST (4-124): 2.76e-41: 135: 68.50		H4_YEAST (18-103): 5.86e-41: 132: 90.70