HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: ROA0 (Q13151)
Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
Gene: HNRNPA0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	34133714, 35271311
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 305
+	Hs
		446505 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		609719 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		ROA2_HUMAN (2-297): 6.2e-78: 242: 42.42
+	Hs
		47724 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		MSI1H_HUMAN (3-304): 4.84e-61: 199: 29.56
+	Hs
		47770 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		PABP4_HUMAN (5-185): 2.85e-44: 161: 19.67
+	Hs
		47742 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Hs
		446486 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		453160 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		446545 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		ROA3_HUMAN (89-183): 5.41e-23: 99.3: 34.74
+	Hs
		446739 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		DAZP1_HUMAN (2-96): 1.3e-19: 90: 31.58
+	Hs
		320958 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		446628 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		161940 SNRPA_HUMAN (1-282): 4.82e-60: 193: 100.00		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91
+	Hs
		643501 PTBP1_HUMAN (1-281): 2.58e-55: 189: 20.42		HNRPD_HUMAN (3-83): 6.84e-16: 78.8: 28.40
+	Hs
		321163 PTBP3_HUMAN (2-281): 3.29e-49: 172: 19.44		DAZP1_HUMAN (2-96): 1.3e-19: 90: 31.58
+	Hs
		516339 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		PABP1_HUMAN (5-186): 8.2e-43: 157: 19.57
+	Sc
		376696 RU1A_YEAST (1-281): 3.81e-48: 163: 20.42		PABP_YEAST (1-79): 6.35e-16: 79.7: 27.50
+	Hs
		47839 RBM47_HUMAN (12-281): 2.3e-39: 146: 18.68		DAZP1_HUMAN (2-96): 1.3e-19: 90: 31.58
+	Sc
		376694 PUB1_YEAST (11-282): 2.91e-39: 144: 18.25		PABP_YEAST (1-79): 6.35e-16: 79.7: 27.50
+	Hs
		453107 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		ROA1_HUMAN (85-183): 1.84e-26: 108: 33.33
+	Hs
		161948 PABP1_HUMAN (10-219): 3.06e-20: 92.2: 15.09		HNRDL_HUMAN (3-88): 1.69e-15: 78.1: 27.91