HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30021884, 39501047
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 1593
+	Hs
		446708 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		MYH10_HUMAN (1057-1592): 1.01e-50: 200: 10.75
+	Hs
		446707 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		MYH9_HUMAN (1060-1592): 1.43e-48: 193: 10.09
+	Hs
		447165 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		RBBP6_HUMAN (1091-1592): 7.8e-28: 125: 13.16
+	Hs
		447008 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		EIF3A_HUMAN (1162-1555): 7.15e-21: 102: 9.07