HitPredict

Interactor 1: SCR (P09077)
Homeotic protein Sex combs reduced
Gene: SCR

Interactor 2: TSH (P22265)
Protein teashirt
Gene: TSH

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	25869471, 17524390
Identification Methods	protein complementation assay, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007494 - midgut development GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 417 Dm			1 954
+	Dm
		367175 ANTP_DROME (95-404): 6.77e-36: 137: 36.05		TSH_DROME (1-954): 0: 676: 100.00
+	Dm
		606524 UBX_DROME (178-385): 2.21e-30: 122: 32.86		TSH_DROME (1-954): 0: 676: 100.00
+	Dm
		606521 ABDA_DROME (305-382): 1.53e-23: 104: 65.91		TSH_DROME (1-954): 0: 676: 100.00
+	Dm
		950039 UBX_DROME (178-385): 2.21e-30: 122: 32.86		TIPT_DROME (1-860): 3.15e-120: 393: 31.84
+	Dm
		668273 ABDA_DROME (305-382): 1.53e-23: 104: 65.91		TIPT_DROME (1-860): 3.15e-120: 393: 31.84
+	Hs
		882142 GSC_HUMAN (202-393): 8.42e-27: 109: 20.57		KMT2C_HUMAN (241-918): 5.27e-09: 62.6: 12.78