Interactor 1: INSR (P09208)
Insulin-like receptor (dIR) (dInr) (EC 2.7.10.1) (Insulin receptor homolog) (dIRH) (Receptor protein-tyrosine kinase InR) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta 1 (Insulin-like receptor subunit beta 170 kDa form) (beta170); Insulin-like receptor subunit beta 2 (Insulin-like receptor subunit beta 90 kDa form) (beta90); 60 kDa C-terminal fragment (Insulin-like receptor free C-terminus)]
Gene: InR

Interactor 2: INSL5 (Q7KUD5)
Probable insulin-like peptide 5 (dILP5) (Insulin-related peptide 5) [Cleaved into: Probable insulin-like peptide 5 A chain; Probable insulin-like peptide 5 B chain]
Gene: Ilp5

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 20974844
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Furin-like~Insulin, Insulin~Recep_L_domain
Common GO terms GO:0007626 - locomotory behavior
GO:0008286 - insulin receptor signaling pathway
GO:0033500 - carbohydrate homeostasis
GO:0060180 - female mating behavior
GO:0061964 - negative regulation of entry into reproductive diapause
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2144
Dm

1 108
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024