Protein: HAP2
Transcriptional activator HAP2

Gene: HAP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 148
UniProt ID: P06774

Gene Ontology (top 5):
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006109 - regulation of carbohydrate metabolic process
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

448214

HAP5
Transcriptional activator HAP5

11

20

Small-scale

0.979

High

448122

HAP3
Transcriptional activator HAP3

8

11

Small-scale

0.964

High

448226

ATG17
Autophagy-related protein 17

2

0

High-throughput

0.606

High

448124

HAP4
Transcriptional activator HAP4

2

0

Small-scale

0.582

High

448249

H2AZ
Histone H2A.Z

1

1

High-throughput

0.575

High

381357

H2B2
Histone H2B.2

1

0

High-throughput

0.546

High

419545

H2A2
Histone H2A.2

1

0

High-throughput

0.546

High

448206

H3
Histone H3

1

0

High-throughput

0.546

High

448149

IMB3
Importin subunit beta-3

1

2

High-throughput

0.536

High

448207

ARP4
Actin-related protein 4

1

1

High-throughput

0.536

High

448142

BUD14
Bud site selection protein 14

1

0

High-throughput

0.518

High

448157

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.518

High

448215

STD1
Protein STD1

1

0

High-throughput

0.518

High

366747

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.513

High

448115

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

448137

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.513

High

448161

YRA2
RNA annealing protein YRA2

1

0

High-throughput

0.513

High

448162

SA190
SIT4-associating protein SAP190

1

0

High-throughput

0.513

High

448173

DPO5
rDNA transcriptional regulator POL5

1

0

High-throughput

0.513

High

448174

NOP16
Nucleolar protein 16

1

0

High-throughput

0.513

High

448176

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.513

High

448180

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

448184

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.513

High

448188

NMD5
Nonsense-mediated mRNA decay protein 5

1

0

High-throughput

0.513

High

448191

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.513

High

448194

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

448230

ASA1
ASTRA-associated protein 1

1

0

High-throughput

0.513

High

448236

YTM1
Ribosome biogenesis protein YTM1

1

0

High-throughput

0.513

High

448240

SPEE
Spermidine synthase SPE3

1

0

High-throughput

0.513

High

448241

ATG29
Autophagy-related protein 29

1

0

High-throughput

0.513

High

448242

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.513

High

448248

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

448175

IMB4
Importin subunit beta-4

1

2

High-throughput

0.500

High

448129

ADT3
ADP,ATP carrier protein 3

1

1

High-throughput

0.489

High

408264

GAL1
Galactokinase

1

0

High-throughput

0.479

High

448138

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.479

High

448145

BMH1
Protein BMH1

1

0

High-throughput

0.479

High

448141

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

448171

PCF11
Protein PCF11

1

2

High-throughput

0.457

High

366874

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

416335

HXKA
Hexokinase-1

1

1

High-throughput

0.457

High

448126

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.457

High

448128

HXKG
Glucokinase-1

1

1

High-throughput

0.457

High

448130

ADT2
ADP,ATP carrier protein 2

1

1

High-throughput

0.457

High

448113

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

448118

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

448119

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

448121

TBP
TATA-box-binding protein

1

1

High-throughput

0.445

High

448134

SNF2
Transcription regulatory protein SNF2

1

5

High-throughput

0.445

High

448136

MCM3
DNA replication licensing factor MCM3

1

2

High-throughput

0.445

High

448140

RSC6
Chromatin structure-remodeling complex protein RSC6

1

1

High-throughput

0.445

High

448146

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.445

High

448147

MCM5
Minichromosome maintenance protein 5

1

3

High-throughput

0.445

High

448148

BTAF1
TATA-binding protein-associated factor MOT1

1

5

High-throughput

0.445

High

448154

SWI3
SWI/SNF complex subunit SWI3

1

4

High-throughput

0.445

High

448155

STH1
Nuclear protein STH1/NPS1

1

5

High-throughput

0.445

High

448156

CHD1
Chromo domain-containing protein 1

1

1

High-throughput

0.445

High

448158

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

1

High-throughput

0.445

High

448159

SPT7
SAGA complex subunit SPT7

1

3

High-throughput

0.445

High

448165

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

3

High-throughput

0.445

High

448166

STP2
Transcription factor STP2

1

1

High-throughput

0.445

High

448168

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.445

High

448177

ATAD2
ATPase histone chaperone YTA7

1

1

High-throughput

0.445

High

448182

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

1

High-throughput

0.445

High

448186

RSC8
Chromatin structure-remodeling complex protein RSC8

1

4

High-throughput

0.445

High

448195

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

1

High-throughput

0.445

High

448196

MCM6
DNA replication licensing factor MCM6

1

2

High-throughput

0.445

High

448197

INO80
Chromatin-remodeling ATPase INO80

1

3

High-throughput

0.445

High

448203

SNF12
Transcription regulatory protein SNF12

1

1

High-throughput

0.445

High

448210

STP1
Transcription factor STP1

1

1

High-throughput

0.445

High

448212

ADA2
SAGA complex subunit ADA2

1

4

High-throughput

0.445

High

448218

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

2

High-throughput

0.445

High

448219

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.445

High

448223

ARP9
Actin-like protein ARP9

1

1

High-throughput

0.445

High

448228

RSC3
Chromatin structure-remodeling complex protein RSC3

1

1

High-throughput

0.445

High

448234

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

5

High-throughput

0.445

High

448244

ARP8
Actin-like protein ARP8

1

1

High-throughput

0.445

High

448246

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.445

High

448221

ELP6
Elongator complex protein 6

1

0

High-throughput

0.438

High

448233

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

381786

H4
Histone H4

1

0

High-throughput

0.426

High

448114

SPT3
SAGA complex subunit SPT3

1

0

High-throughput

0.426

High

448123

STE12
Protein STE12

1

0

High-throughput

0.426

High

448131

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

0

High-throughput

0.426

High

448132

GLN3
Nitrogen regulatory protein GLN3

1

0

High-throughput

0.426

High

448133

DAL81
Transcriptional activator protein DAL81

1

0

High-throughput

0.426

High

448135

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.426

High

448139

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.426

High

448143

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.426

High

448144

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.426

High

448150

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

448151

HIR2
Protein HIR2

1

0

High-throughput

0.426

High

448152

NGG1
SAGA complex subunit NGG1

1

0

High-throughput

0.426

High

448160

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.426

High

448164

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.426

High

448169

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

0

High-throughput

0.426

High

448170

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.426

High

448179

YAP5
AP-1-like transcription factor YAP5

1

0

High-throughput

0.426

High

448183

EPL1
Enhancer of polycomb-like protein 1

1

0

High-throughput

0.426

High

448185

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.426

High

448187

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.426

High

448192

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.426

High

448193

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

448198

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.426

High

448200

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.426

High

448201

H1
Histone H1

1

0

High-throughput

0.426

High

448205

ACT
Actin

1

0

High-throughput

0.426

High

448209

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

448213

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

448216

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

448217

TAF8
Transcription initiation factor TFIID subunit 8

1

0

High-throughput

0.426

High

448222

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.426

High

448224

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.426

High

448229

ELP1
Elongator complex protein 1

1

0

High-throughput

0.426

High

448231

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

448237

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

0

High-throughput

0.426

High

448238

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.426

High

448239

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.426

High

448243

RFM1
Repression factor of MSEs protein 1

1

0

High-throughput

0.426

High

448116

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.407

High

448199

RSC1
Chromatin structure-remodeling complex subunit RSC1

1

6

High-throughput

0.407

High

448211

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

4

High-throughput

0.407

High

448227

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

6

High-throughput

0.407

High

448190

ECL1
Extender of the chronological lifespan protein 1

1

0

High-throughput

0.282

High

448208

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.282

High

448117

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.279

Low

448153

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.279

Low

448163

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

448167

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.279

Low

448172

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.279

Low

448178

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.279

Low

448202

SSK2
MAP kinase kinase kinase SSK2

1

0

High-throughput

0.279

Low

448204

MTQ1
Mitochondrial MRF1 N(5)-glutamine methyltransferase MTQ1

1

0

High-throughput

0.279

Low

448220

GRH1
GRASP65 homolog protein 1

1

0

High-throughput

0.279

Low

448245

ATG31
Autophagy-related protein 31

1

0

High-throughput

0.279

Low

448247

AVL9
Late secretory pathway protein AVL9

1

0

High-throughput

0.265

Low

368541

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

386513

TBB
Tubulin beta chain

1

0

High-throughput

0.261

Low

448120

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

448127

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.261

Low

448181

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.261

Low

448232

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

448125

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

448225

NCS1
Calcium-binding protein NCS-1

1

0

High-throughput

0.238

Low

448235

SOG2
Leucine-rich repeat-containing protein SOG2

1

0

High-throughput

0.238

Low

149184

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.232

Low

448189

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025