HitPredict

Interactor 1: GSTP1 (P09211)
Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1)
Gene: GSTP1

Interactor 2: MK08 (P45983)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (JNK-46) (Stress-activated protein kinase 1c) (SAPK1c) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: MAPK8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	35027562, 26429914, 11279197, 16636664
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043066 - negative regulation of apoptotic process GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 210 Hs			1 427
+	Mm
		622853 GSTA4_MOUSE (2-206): 7.09e-58: 183: 31.43		MK10_MOUSE (1-427): 5.84e-164: 470: 89.46
+	Hs
		597485 GSTM3_HUMAN (2-210): 1.79e-57: 182: 29.82		MK08_HUMAN (1-427): 6.2e-164: 469: 100.00
+	Mm
		622855 GSTA4_MOUSE (2-206): 7.09e-58: 183: 31.43		MK09_MOUSE (1-427): 1.29e-160: 460: 81.50
+	Mm
		622854 GSTA4_MOUSE (2-206): 7.09e-58: 183: 31.43		MK08_MOUSE (1-381): 7.75e-152: 437: 99.48
+	Hs
		448293 GSTP1_HUMAN (1-210): 1.79e-67: 207: 100.00		CDK2_HUMAN (23-329): 1.82e-136: 394: 33.23
+	Hs
		448345 GSTP1_HUMAN (1-210): 1.79e-67: 207: 100.00		MK14_HUMAN (4-365): 2.33e-130: 381: 46.03
+	Ce
		999512 GST5_CAEEL (1-201): 1.81e-53: 171: 25.12		JNK1_CAEEL (1-366): 1.19e-135: 398: 68.21
+	Hs
		448294 GSTP1_HUMAN (1-210): 1.79e-67: 207: 100.00		MK01_HUMAN (20-359): 2.94e-84: 263: 42.98