HitPredict

Interactor 1: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Interactor 2: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	24529377
Identification Methods	anti bait coimmunoprecipitation, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 135 Hs			1 1356
+	Hs
		449252 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		PTK7_HUMAN (329-882): 3.37e-42: 170: 13.58
+	Hs
		449182 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38
+	Hs
		449210 LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00		VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93
+	Hs
		572301 LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47		VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93
+	Hs
		121093 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54
+	Hs
		121120 LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13		VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93