HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: HXD10 (P28358)
Homeobox protein Hox-D10 (Homeobox protein Hox-4D) (Homeobox protein Hox-4E)
Gene: HOXD10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8890171
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0017053 - transcription repressor complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 340
+	Hs
		449565 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		HXD11_HUMAN (121-339): 1.26e-33: 128: 27.27
+	Hs
		449512 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		HXD8_HUMAN (236-331): 1.76e-33: 126: 44.44
+	Hs
		449564 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		HXA10_HUMAN (5-340): 4.48e-32: 125: 38.62
+	Hs
		175781 HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60		Q6FHY5_HUMAN (96-336): 3.91e-34: 129: 20.87
+	Hs
		449499 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		HXC6_HUMAN (128-325): 1.47e-30: 117: 24.75
+	Hs
		175757 HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60		MEOX1_HUMAN (96-337): 1.55e-28: 112: 20.66
+	Hs
		449555 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		HXD9_HUMAN (254-318): 3.46e-24: 103: 73.85
+	Hs
		175758 HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60		MEOX2_HUMAN (96-336): 2.32e-27: 110: 20.00
+	Hs
		595592 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		HXA5_HUMAN (161-339): 2e-34: 128: 27.03
+	Dm
		950090 Q9VUD3_DROME (2-95): 4.18e-28: 112: 21.28		UBX_DROME (121-327): 2.1e-27: 112: 25.82
+	Hs
		567820 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		HXB9_HUMAN (92-331): 8.21e-31: 118: 32.92
+	Hs
		198797 SOX8_HUMAN (7-89): 7.32e-22: 94.4: 18.07		HXC11_HUMAN (73-339): 9.52e-33: 125: 27.34
+	Dm
		115538 M9PFG6_DROME (7-95): 5.32e-26: 105: 21.35		UBX_DROME (121-327): 2.1e-27: 112: 25.82
+	Dm
		114548 M9PCZ7_DROME (3-84): 4.91e-25: 104: 23.17		UBX_DROME (121-327): 2.1e-27: 112: 25.82
+	Dm
		668309 Q9VUD3_DROME (2-95): 4.18e-28: 112: 21.28		ABDA_DROME (267-326): 4.56e-17: 84: 68.33
+	Hs
		617325 SP100_HUMAN (25-178): 1.23e-34: 131: 87.66		ZFHX4_HUMAN (213-334): 3.92e-09: 60.3: 14.06
+	Dm
		115535 M9PFG6_DROME (7-95): 5.32e-26: 105: 21.35		ABDA_DROME (267-326): 4.56e-17: 84: 68.33
+	Dm
		114546 M9PCZ7_DROME (3-84): 4.91e-25: 104: 23.17		ABDA_DROME (267-326): 4.56e-17: 84: 68.33
+	Hs
		1199928 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		ZFHX4_HUMAN (213-334): 3.92e-09: 60.3: 14.06
+	Hs
		818205 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		ZFHX4_HUMAN (213-334): 3.92e-09: 60.3: 14.06