HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: GNL3 (Q9BVP2)
Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin)
Gene: GNL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29721183
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005615 - extracellular space GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 549
+	Hs
		643398 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		GNL3_HUMAN (1-549): 0: 544: 100.00
+	Hs
		617367 SP100_HUMAN (25-178): 1.23e-34: 131: 87.66		GNL3_HUMAN (1-549): 0: 544: 100.00
+	Hs
		996871 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		GNL3_HUMAN (1-549): 0: 544: 100.00
+	Hs
		818418 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		GNL3_HUMAN (1-549): 0: 544: 100.00
+	Ce
		136700 SSP1B_CAEEL (91-208): 5.6e-18: 83.7: 32.80		GNL3_CAEEL (1-539): 3.96e-130: 392: 31.63
+	Hs
		958900 TFAM_HUMAN (95-186): 2.95e-09: 57.1: 17.39		NOG2_HUMAN (8-492): 4.75e-113: 354: 24.80
+	Hs
		643399 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		LSG1_HUMAN (50-256): 5.15e-48: 178: 22.12