HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: CYP7 (P47103)
Peptidyl-prolyl cis-trans isomerase CYP7 (PPIase CYP7) (EC 5.2.1.8) (Rotamase CYP7)
Gene: CPR7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	9819422
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding GO:0042026 - protein refolding GO:0051082 - unfolded protein binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 649 Sc			1 393
+	Hs
		503968 HSP7C_HUMAN (2-649): 0: 946: 72.53		PPID_HUMAN (3-393): 3.44e-113: 336: 30.10
+	Ca
		784139 HSP71_CANAL (1-606): 0: 968: 85.83		PPID_CANAL (1-393): 5.28e-104: 313: 37.06
+	Sc
		494338 HSP72_YEAST (1-649): 0: 941: 78.89		CYP7_YEAST (1-393): 1.52e-111: 333: 100.00
+	Sc
		491698 HSP71_YEAST (1-649): 0: 939: 79.35		CYP7_YEAST (1-393): 1.52e-111: 333: 100.00
+	Ca
		804455 HSP72_CANAL (1-649): 0: 952: 80.43		PPID_CANAL (1-393): 5.28e-104: 313: 37.06
+	Sc
		605366 HSP74_YEAST (1-649): 0: 924: 86.75		CYP7_YEAST (1-393): 1.52e-111: 333: 100.00
+	Sc
		494588 HSP72_YEAST (1-649): 0: 941: 78.89		PPID_YEAST (2-393): 2.65e-95: 291: 37.88
+	Sc
		491994 HSP71_YEAST (1-649): 0: 939: 79.35		PPID_YEAST (2-393): 2.65e-95: 291: 37.88
+	Hs
		503513 HSP7C_HUMAN (2-649): 0: 946: 72.53		PPIF_HUMAN (4-198): 3.48e-72: 226: 40.31
+	Sc
		493093 HSP72_YEAST (1-649): 0: 941: 78.89		CYPH_YEAST (6-179): 1.21e-64: 205: 41.14
+	Sc
		490206 HSP71_YEAST (1-649): 0: 939: 79.35		CYPH_YEAST (6-179): 1.21e-64: 205: 41.14
+	Sc
		449937 HSP73_YEAST (1-649): 0: 948: 100.00		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79
+	Sc
		493331 HSP72_YEAST (1-649): 0: 941: 78.89		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79
+	Sc
		490493 HSP71_YEAST (1-649): 0: 939: 79.35		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79
+	Sc
		605308 HSP74_YEAST (1-649): 0: 924: 86.75		CYPC_YEAST (5-196): 4.77e-59: 191: 36.79