HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: JUND (P17535)
Transcription factor JunD (Transcription factor AP-1 subunit JunD)
Gene: JUND

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 347
+	Hs
		418871 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		JUND_HUMAN (1-347): 5.24e-75: 236: 100.00
+	Hs
		401292 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		JUN_HUMAN (1-347): 1.06e-67: 217: 49.17
+	Hs
		401268 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		JUN_HUMAN (1-347): 1.06e-67: 217: 49.17
+	Mm
		404129 TPM1_MOUSE (1-284): 1.72e-44: 153: 99.65		JUN_MOUSE (1-347): 1.96e-67: 216: 49.59
+	Hs
		418870 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		JUNB_HUMAN (1-347): 1.77e-64: 209: 38.65
+	Mm
		404130 TPM2_MOUSE (1-284): 2.06e-38: 138: 85.92		JUN_MOUSE (1-347): 1.96e-67: 216: 49.59
+	Dm
		419095 TPM1_DROME (1-281): 3.07e-56: 186: 44.78		JRA_DROME (1-340): 2.37e-45: 158: 29.65
+	Hs
		451186 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82
+	Hs
		418865 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82
+	Hs
		547777 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		ATF2_HUMAN (22-347): 5.27e-47: 168: 19.82
+	Hs
		3155 A0A0S2Z4G4_HUMAN (1-242): 2.69e-14: 72.7: 23.97		JUN_HUMAN (1-347): 1.06e-67: 217: 49.17
+	Hs
		579190 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		ATF3_HUMAN (190-334): 1.8e-13: 69.8: 20.13