HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: HOME1 (Q86YM7)
Homer protein homolog 1 (Homer-1)
Gene: HOMER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 354
+	Hs
		418997 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		HOME1_HUMAN (1-354): 4.46e-62: 204: 100.00
+	Hs
		419058 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		HOME2_HUMAN (1-351): 8.57e-56: 187: 51.00
+	Hs
		451288 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		DLG5_HUMAN (107-349): 5.1e-10: 63.1: 13.81
+	Mm
		358674 LAMC1_MOUSE (1-283): 1.81e-12: 69.6: 14.97		LAMB1_MOUSE (101-352): 3.86e-36: 141: 16.60
+	Rn
		1186812 MRCKB_RAT (1-283): 1.5e-32: 128: 19.60		MRCKB_RAT (94-347): 1.99e-10: 64.3: 13.31
+	Rn
		222476 MRCKB_RAT (1-283): 1.5e-32: 128: 19.60		MRCKA_RAT (165-354): 2.09e-09: 61.2: 14.74
+	Hs
		1137917 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		MRCKB_HUMAN (94-347): 1.37e-09: 62: 12.95
+	Hs
		1137871 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		MRCKA_HUMAN (67-345): 9.31e-09: 59.3: 12.63
+	Rn
		222472 MRCKA_RAT (68-280): 4.85e-09: 59.2: 15.96		MRCKA_RAT (165-354): 2.09e-09: 61.2: 14.74