HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21951318
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 530
+	Hs
		502858 LAMC1_HUMAN (2-284): 2.65e-53: 188: 18.34		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		419012 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		433179 LAMB1_HUMAN (1-248): 3.31e-37: 141: 23.44		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		932032 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368850 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368825 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369789 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377051 LAMC1_HUMAN (2-284): 2.65e-53: 188: 18.34		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		418875 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		451180 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		418856 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487504 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487321 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59