HitPredict

Interactor 1: CLCB (P09497)
Clathrin light chain B (Lcb)
Gene: CLTB

Interactor 2: DAB2 (P98082)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)
Gene: DAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 770
+	Hs
		451419 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Hs
		451394 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		451651 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		451630 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		NUMBL_HUMAN (18-585): 6.55e-41: 161: 13.54
+	Hs
		451598 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		DP13A_HUMAN (15-259): 1.71e-36: 148: 11.91
+	Hs
		451763 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		NUMBL_HUMAN (18-585): 6.55e-41: 161: 13.54
+	Hs
		253526 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		CAPON_HUMAN (19-299): 8.52e-35: 141: 13.91
+	Hs
		451754 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		DP13A_HUMAN (15-259): 1.71e-36: 148: 11.91
+	Hs
		253527 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		CAPON_HUMAN (19-299): 8.52e-35: 141: 13.91
+	Hs
		203201 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		SYNJ1_HUMAN (196-735): 1.47e-19: 96.5: 13.64
+	Hs
		203202 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		SYNJ1_HUMAN (196-735): 1.47e-19: 96.5: 13.64