HitPredict

Interactor 1: CLCB (P09497)
Clathrin light chain B (Lcb)
Gene: CLTB

Interactor 2: AP1B1 (Q10567)
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Gene: AP1B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 949
+	Hs
		451428 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP1B1_HUMAN (1-949): 0: 978: 100.00
+	Hs
		451417 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		451663 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		321466 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP2A1_HUMAN (12-943): 0: 677: 18.58
+	Hs
		321467 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		AP2A1_HUMAN (12-943): 0: 677: 18.58
+	Hs
		302090 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP2A2_HUMAN (12-945): 0: 625: 18.33
+	Hs
		302091 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		AP2A2_HUMAN (12-945): 0: 625: 18.33
+	Hs
		212587 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP1G1_HUMAN (12-822): 0: 556: 17.29
+	Hs
		212588 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		AP1G1_HUMAN (12-822): 0: 556: 17.29
+	Hs
		119912 CLCA_HUMAN (13-227): 2.26e-100: 293: 61.23		AP3B1_HUMAN (6-620): 6.51e-156: 489: 27.73
+	Hs
		119913 CLCB_HUMAN (1-229): 2.06e-95: 279: 100.00		AP3B1_HUMAN (6-620): 6.51e-156: 489: 27.73