HitPredict

Interactor 1: H2A (P09588)
Histone H2A
Gene: his-3

Interactor 2: H2B4 (Q27876)
Probable histone H2B 4
Gene: his-48

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26952210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 127 Ce			1 123
+	Hs
		1216239 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2B1H_HUMAN (3-123): 9.01e-50: 156: 80.49
+	Hs
		1087239 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2B2E_HUMAN (3-123): 1.38e-49: 155: 79.68
+	Hs
		707681 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2B1B_HUMAN (3-123): 2.55e-49: 154: 78.86
+	Hs
		886151 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2B1D_HUMAN (3-123): 3.95e-49: 154: 80.49
+	Hs
		918497 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2B1C_HUMAN (3-123): 2.61e-49: 154: 80.49
+	Hs
		1087075 H2A2C_HUMAN (1-126): 8.56e-63: 189: 84.92		H2B1H_HUMAN (3-123): 9.01e-50: 156: 80.49
+	Hs
		617950 H2A2C_HUMAN (1-126): 8.56e-63: 189: 84.92		H2B1O_HUMAN (3-123): 5.27e-50: 156: 79.68
+	Hs
		617974 H2AJ_HUMAN (1-126): 6.73e-63: 189: 85.71		H2B1O_HUMAN (3-123): 5.27e-50: 156: 79.68
+	Hs
		1087007 H2A2C_HUMAN (1-126): 8.56e-63: 189: 84.92		H2B2E_HUMAN (3-123): 1.38e-49: 155: 79.68
+	Hs
		1087366 H2A1J_HUMAN (1-125): 1.01e-62: 189: 84.80		H2B2E_HUMAN (3-123): 1.38e-49: 155: 79.68
+	Hs
		1087377 H2AJ_HUMAN (1-126): 6.73e-63: 189: 85.71		H2B2E_HUMAN (3-123): 1.38e-49: 155: 79.68
+	Hs
		241623 H2A1J_HUMAN (1-125): 1.01e-62: 189: 84.80		H2B1K_HUMAN (3-123): 2.97e-49: 154: 79.68
+	Hs
		886117 H2A2C_HUMAN (1-126): 8.56e-63: 189: 84.92		H2B1D_HUMAN (3-123): 3.95e-49: 154: 80.49
+	Hs
		886186 H2AJ_HUMAN (1-126): 6.73e-63: 189: 85.71		H2B1D_HUMAN (3-123): 3.95e-49: 154: 80.49
+	Hs
		1216224 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2B3B_HUMAN (3-123): 1.55e-47: 150: 73.98
+	Xl
		355252 Q6AZJ8_XENLA (1-126): 8.65e-63: 189: 85.71		H2B11_XENLA (3-123): 1.89e-48: 153: 80.49
+	Hs
		1087049 H2A2C_HUMAN (1-126): 8.56e-63: 189: 84.92		H2B3B_HUMAN (3-123): 1.55e-47: 150: 73.98
+	Hs
		1216241 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2B1A_HUMAN (6-123): 5.81e-44: 141: 82.20
+	Hs
		1087076 H2A2C_HUMAN (1-126): 8.56e-63: 189: 84.92		H2B1A_HUMAN (6-123): 5.81e-44: 141: 82.20
+	Hs
		1187486 H2A2B_HUMAN (1-126): 6.03e-64: 192: 87.30		H2BWT_HUMAN (3-120): 2.64e-42: 138: 41.67