HitPredict

Interactor 1: DLDH (P09622)
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
Gene: DLD

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29128334
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 245
+	Hs
		452720 DLDH_HUMAN (1-509): 0: 543: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Mm
		139766 DLDH_MOUSE (1-509): 0: 537: 94.89		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Mm
		139765 DLDH_MOUSE (1-509): 0: 537: 94.89		1433E_MOUSE (2-241): 9.9e-144: 403: 68.18
+	Hs
		452635 DLDH_HUMAN (1-509): 0: 543: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		452645 DLDH_HUMAN (1-509): 0: 543: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Mm
		139767 DLDH_MOUSE (1-509): 0: 537: 94.89		1433T_MOUSE (1-245): 8.98e-140: 393: 79.18
+	Mm
		139797 DLDH_MOUSE (1-509): 0: 537: 94.89		1433B_MOUSE (1-242): 3.77e-128: 364: 87.19
+	Hs
		452715 DLDH_HUMAN (1-509): 0: 543: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		452746 DLDH_HUMAN (1-509): 0: 543: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Mm
		139763 DLDH_MOUSE (1-509): 0: 537: 94.89		1433G_MOUSE (1-240): 2.37e-108: 314: 74.59