HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25324306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 639
+	Hs
		380541 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94
+	Hs
		453276 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		KRT83_HUMAN (83-491): 2.11e-86: 280: 49.02
+	Hs
		453117 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48
+	Hs
		380439 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22
+	Hs
		453213 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61
+	Hs
		453418 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C79_HUMAN (32-568): 4.69e-80: 264: 55.35
+	Hs
		359456 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22