HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 768
+	Hs
		201667 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042258 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		162039 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		609851 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		162040 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		453345 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		609852 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043512 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		162041 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		453342 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041143 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		162037 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		609849 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		453343 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041432 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		162038 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		609850 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		453518 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1274014 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		162106 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CUL5_HUMAN (25-768): 0: 597: 23.77