HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: CIRBP (Q14011)
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene: CIRBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex and 1 others more... GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 172
+	Hs
		453291 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		453331 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP4_HUMAN (7-170): 1.39e-28: 112: 20.12
+	Hs
		453107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		609811 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		162035 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP4_HUMAN (7-170): 1.39e-28: 112: 20.12
+	Hs
		161948 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		516358 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		516424 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		453192 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		453267 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		745188 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		453229 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		ROA3_HUMAN (7-92): 2.98e-14: 70.9: 43.02
+	Hs
		161978 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		609738 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		745100 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		852075 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		ROA3_HUMAN (7-92): 2.98e-14: 70.9: 43.02
+	Hs
		609770 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ROA3_HUMAN (7-92): 2.98e-14: 70.9: 43.02
+	Hs
		516689 PABP3_HUMAN (6-193): 6.86e-35: 137: 17.90		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		516663 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		745277 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35