Protein: YEN1
Holliday junction resolvase YEN1 (EC 3.1.-.-)

Gene: YEN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 34
UniProt ID: P40028

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0000400 - four-way junction DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

586461

PCNA
Proliferating cell nuclear antigen

1

7

High-throughput

0.691

High

364559

CDK1
Cyclin-dependent kinase 1

3

4

Small-scale

0.670

High

817317

CDC14
Tyrosine-protein phosphatase CDC14

2

1

Small-scale

0.624

High

718943

CGS5
S-phase entry cyclin-5

2

7

High-throughput

0.611

High

745476

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

Small-scale

0.558

High

803557

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.515

High

817319

FKBP4
FK506-binding protein 4

1

0

High-throughput

0.513

High

817315

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

817321

SIZ2
E3 SUMO-protein ligase SIZ2

1

2

Small-scale

0.501

High

403524

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

High-throughput

0.500

High

453617

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.500

High

518034

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.500

High

699406

CIN8
Kinesin-like protein CIN8

1

1

Small-scale

0.481

High

782133

T2EB
Transcription initiation factor IIE subunit beta

1

1

Small-scale

0.481

High

813401

PES4
Protein PES4

1

2

Small-scale

0.481

High

817320

ULS1
ATP-dependent helicase ULS1

1

1

Small-scale

0.481

High

817322

SMT3
Ubiquitin-like protein SMT3

1

4

Small-scale

0.481

High

813764

OAF1
Oleate-activated transcription factor 1

1

0

Small-scale

0.460

High

817316

NIS1
Protein NIS1

1

0

Small-scale

0.460

High

817323

MPC70
Sporulation-specific protein 21

1

0

Small-scale

0.460

High

751410

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

392792

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

481633

HSP73
Heat shock protein SSA3

1

8

High-throughput

0.445

High

524068

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

545012

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

676032

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

817314

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

782343

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

367035

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.261

Low

368677

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

817202

FIR1
Factor interacting with REF2

1

0

Small-scale

0.251

Low

513504

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.249

Low

515264

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.249

Low

817318

AAD16
Putative aryl-alcohol dehydrogenase AAD16

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025