HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: HNRL2 (Q1KMD3)
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (Scaffold-attachment factor A2) (SAF-A2)
Gene: HNRNPUL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25324306, 26496610, 17643375
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 747
+	Hs
		609892 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		HNRL2_HUMAN (1-747): 0: 781: 100.00
+	Hs
		1020266 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		HNRL2_HUMAN (1-747): 0: 781: 100.00
+	Hs
		453578 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		HNRL1_HUMAN (1-661): 0: 645: 42.07
+	Mm
		857311 TIA1_MOUSE (99-193): 5.17e-09: 59.4: 17.71		HNRL2_MOUSE (1-747): 0: 783: 95.05
+	Hs
		453295 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Hs
		162014 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Hs
		609815 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Hs
		962310 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Hs
		962074 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Hs
		962056 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		HNRPU_HUMAN (1-687): 0: 611: 41.71
+	Hs
		453556 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		RANB9_HUMAN (199-534): 1.5e-85: 287: 18.91
+	Hs
		453499 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		DDX1_HUMAN (161-539): 6.94e-84: 283: 22.86
+	Hs
		610012 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		RANB9_HUMAN (199-534): 1.5e-85: 287: 18.91
+	Hs
		609911 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		RN123_HUMAN (278-441): 3.42e-39: 158: 24.85