Protein: CARB
Carbamoyl phosphate synthase arginine-specific large chain (CPS) (CPSase) (CPSase-arg) (EC 6.3.4.16) (EC 6.3.5.5) (Ammonium-dependent carbamoyl phosphate synthetase) (Arginine-specific carbamoyl phosphate synthetase, ammonia chain) (Carbamoyl phosphate synthase A) (CPS-A) (Glutamine-dependent carbamoyl phosphate synthetase)

Gene: CARB, CPA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 71
UniProt ID: P03965

Gene Ontology (top 5):
GO:0004087 - carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005951 - carbamoyl-phosphate synthase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

399326

CARA
Carbamoyl phosphate synthase arginine-specific small chain

4

11

Small-scale

0.892

High

399327

PYR1
Multifunctional protein URA2

2

19

High-throughput

0.759

High

399349

URA7
CTP synthase 1

2

1

High-throughput

0.759

High

399346

RAD51
DNA repair protein RAD51

2

4

High-throughput

0.621

High

399336

HSC82
ATP-dependent molecular chaperone HSC82

2

8

High-throughput

0.584

High

399373

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

399332

SSB1
Ribosome-associated molecular chaperone SSB1

2

14

High-throughput

0.552

High

399325

FAS1
Fatty acid synthase subunit beta

1

2

High-throughput

0.536

High

399359

PRS6B
26S proteasome regulatory subunit 6B homolog

1

5

High-throughput

0.536

High

399365

DBP8
ATP-dependent RNA helicase DBP8

1

2

High-throughput

0.536

High

399370

RFC2
Replication factor C subunit 2

1

2

High-throughput

0.536

High

399372

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.536

High

399377

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.536

High

399383

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.536

High

399351

HRR25
Casein kinase I homolog HRR25

1

7

High-throughput

0.501

High

399382

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

7

High-throughput

0.501

High

399339

PHO85
Cyclin-dependent protein kinase PHO85

1

8

High-throughput

0.500

High

399343

PP11
Serine/threonine-protein phosphatase PP1-1

1

3

High-throughput

0.500

High

399344

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

1

High-throughput

0.500

High

399353

ARP2
Actin-related protein 2

1

1

High-throughput

0.500

High

368100

THDH
Threonine dehydratase, mitochondrial

1

3

High-throughput

0.489

High

381763

H4
Histone H4

1

5

High-throughput

0.489

High

399335

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

3

High-throughput

0.489

High

399355

EI2BB
Translation initiation factor eIF2B subunit beta

1

3

High-throughput

0.489

High

399364

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.489

High

399384

CMR1
DNA damage-binding protein CMR1

1

13

High-throughput

0.481

High

368209

TRP
Tryptophan synthase

1

1

High-throughput

0.479

High

391944

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.479

High

399322

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

399324

SNF1
Carbon catabolite-derepressing protein kinase

1

5

Small-scale

0.479

High

399333

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

399340

MDHM
Malate dehydrogenase, mitochondrial

1

4

Small-scale

0.479

High

399347

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

399356

ZUO1
Zuotin

1

3

Small-scale

0.479

High

399358

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.479

High

399362

ATG8
Autophagy-related protein 8

1

9

High-throughput

0.479

High

399366

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.479

High

399378

SYRC
Arginine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.479

High

399381

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.479

High

366741

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

399331

AK
Aspartokinase

1

0

High-throughput

0.458

High

399337

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.458

High

399342

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

0

High-throughput

0.458

High

399352

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

399376

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.458

High

399328

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.457

High

386503

TBB
Tubulin beta chain

1

4

High-throughput

0.445

High

394074

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

399323

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

399329

TBA1
Tubulin alpha-1 chain

1

7

High-throughput

0.445

High

399330

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

399334

DHAS
Aspartate-semialdehyde dehydrogenase

1

1

High-throughput

0.445

High

399360

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.445

High

399369

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

399345

SIS1
Protein SIS1

1

4

High-throughput

0.437

High

399350

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

399367

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

399368

GGC1
Mitochondrial GTP/GDP carrier protein 1

1

5

High-throughput

0.437

High

399375

SAP4
SIT4-associating protein SAP4

1

3

High-throughput

0.437

High

359101

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

399338

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

399348

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

5

High-throughput

0.407

High

399354

CDC3
Cell division control protein 3

1

0

High-throughput

0.261

Low

399357

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

399341

TEC1
Ty transcription activator TEC1

1

0

High-throughput

0.249

Low

399361

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

399363

POP7
Ribonucleases P/MRP protein subunit POP7

1

0

High-throughput

0.249

Low

399371

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

399374

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.249

Low

399379

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.249

Low

399380

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025