HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: LARP1 (Q6PKG0)
La-related protein 1 (La ribonucleoprotein domain family member 1)
Gene: LARP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26186194, 25324306, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 1096
+	Hs
		162075 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		1020277 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		453419 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		LAR1B_HUMAN (175-1093): 0: 632: 55.38
+	Hs
		1020271 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		LAR1B_HUMAN (175-1093): 0: 632: 55.38
+	Hs
		453393 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		1104152 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		162065 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		609895 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		403061 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		852076 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		161934 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Hs
		1116542 PABP3_HUMAN (6-193): 6.86e-35: 137: 17.90		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		1116487 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		LARP7_HUMAN (399-925): 2.04e-79: 273: 15.37
+	Hs
		403323 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		LA_HUMAN (400-800): 4.26e-76: 258: 17.43
+	Sc
		376965 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		SLF1_YEAST (165-538): 9.2e-45: 170: 17.19
+	At
		285478 PABP8_ARATH (10-190): 2.89e-34: 135: 22.95		LRP6B_ARATH (205-638): 1.18e-43: 169: 16.06
+	Sc
		376709 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		LHP1_YEAST (379-642): 1.05e-32: 130: 16.13
+	Sc
		376650 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		SRO9_YEAST (183-463): 1.89e-23: 106: 15.92
+	Hs
		1020300 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23
+	Zm
		10866 A0A1D6F8R0_MAIZE (7-362): 2.55e-18: 87.9: 21.91		C0P861_MAIZE (10-383): 4.28e-13: 75.9: 11.77