HitPredict

Interactor 1: FGR (P09769)
Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)
Gene: FGR

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	20098747, 23131831
Identification Methods	pull down, affinity chromatography technology, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0009615 - response to virus GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 419
+	Hs
		412431 FYN_HUMAN (1-527): 0: 607: 69.94		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		523232 SRC_HUMAN (1-527): 0: 602: 65.74		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		411910 LCK_HUMAN (1-526): 0: 559: 51.90		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		434106 LYN_HUMAN (1-524): 0: 553: 53.91		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		411983 FYN_HUMAN (1-527): 0: 607: 69.94		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		433781 LYN_HUMAN (1-524): 0: 553: 53.91		ITSN1_HUMAN (24-403): 1.07e-30: 127: 12.15
+	Hs
		412058 FYN_HUMAN (1-527): 0: 607: 69.94		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		412287 FYN_HUMAN (1-527): 0: 607: 69.94		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89
+	Hs
		411905 LCK_HUMAN (1-526): 0: 559: 51.90		MYO5A_HUMAN (38-342): 1.7e-24: 108: 14.65
+	Hs
		111443 J3QRU1_HUMAN (1-527): 0: 596: 67.83		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		433272 YES_HUMAN (1-527): 0: 596: 67.83		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		523231 SRC_HUMAN (1-527): 0: 602: 65.74		MYH4_HUMAN (21-393): 8.88e-09: 60: 13.44
+	Hs
		411581 LCK_HUMAN (1-526): 0: 559: 51.90		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		433558 LYN_HUMAN (1-524): 0: 553: 53.91		DESP_HUMAN (45-363): 7.32e-21: 97.8: 15.84
+	Hs
		411758 LCK_HUMAN (1-526): 0: 559: 51.90		MRCKA_HUMAN (32-363): 1.19e-13: 75.1: 15.89
+	Hs
		433818 LYN_HUMAN (1-524): 0: 553: 53.91		MRCKA_HUMAN (32-363): 1.19e-13: 75.1: 15.89
+	Hs
		411908 LCK_HUMAN (1-526): 0: 559: 51.90		MRCKB_HUMAN (39-356): 2.85e-10: 64.7: 13.60
+	Hs
		433620 LYN_HUMAN (1-524): 0: 553: 53.91		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93
+	Hs
		434101 LYN_HUMAN (1-524): 0: 553: 53.91		MRCKB_HUMAN (39-356): 2.85e-10: 64.7: 13.60
+	Hs
		724720 BLK_HUMAN (1-524): 0: 532: 54.10		MYH9_HUMAN (11-402): 4.5e-11: 67.3: 9.93