HitPredict

Interactor 1: LOX5 (P09917)
Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34)
Gene: ALOX5

Interactor 2: RNF6 (Q9Y252)
E3 ubiquitin-protein ligase RNF6 (EC 2.3.2.27)
Gene: RNF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031965 - nuclear membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 674 Hs			1 685
+	Hs
		1316997 LOXE3_HUMAN (1-674): 0: 857: 38.49		RNF6_HUMAN (1-685): 9.95e-160: 478: 100.00
+	Hs
		1169186 LOXE3_HUMAN (1-674): 0: 857: 38.49		RN111_HUMAN (126-676): 1.15e-50: 192: 11.13
+	Hs
		259884 LX12B_HUMAN (1-674): 0: 833: 39.32		RNF38_HUMAN (166-675): 4.46e-52: 190: 13.91
+	Hs
		259900 LX12B_HUMAN (1-674): 0: 833: 39.32		RN115_HUMAN (491-683): 7.97e-36: 139: 20.90
+	Hs
		1190158 PK1L2_HUMAN (4-198): 1.79e-29: 127: 20.71		RNF12_HUMAN (1-684): 1.85e-84: 280: 38.95