HitPredict

Interactor 1: UCHL1 (P09936)
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Gene: UCHL1

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32606430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 654
+	Hs
		456478 UCHL1_HUMAN (1-223): 2.52e-103: 299: 100.00		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		503371 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502727 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		714033 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HS71L_HUMAN (24-647): 0: 922: 63.16
+	Hs
		504488 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		564140 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HSP76_HUMAN (25-635): 0: 915: 62.54
+	Hs
		502383 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		871707 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		HSP72_HUMAN (25-636): 0: 905: 64.51