Protein: CCPA
Catabolite control protein A (Glucose-resistance amylase regulator)

Gene: CCPA
Organism: Bacillus subtilis subsp. subtilis str. 168
Interactions: 224
UniProt ID: P25144

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0001216 - DNA-binding transcription activator activity
GO:0001217 - DNA-binding transcription repressor activity
GO:0003700 - DNA-binding transcription factor activity
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476891

PTHP
Phosphocarrier protein HPr

2

0

High-throughput

0.633

High

669446

CCPA
Catabolite control protein A

1

10

High-throughput

0.590

High

669490

CODY
Global transcriptional regulator CodY

1

0

High-throughput

0.545

High

669478

CYSK
Cysteine synthase

1

2

High-throughput

0.445

High

669508

APBC
Iron-sulfur cluster carrier protein

1

1

High-throughput

0.445

High

553686

GLN1A
Glutamine synthetase

1

0

High-throughput

0.426

High

669457

NUSA
Transcription termination/antitermination protein NusA

1

0

High-throughput

0.426

High

90228

YTCI
Uncharacterized acyl--CoA ligase YtcI

1

1

High-throughput

0.407

High

147086

FENR2
Ferredoxin--NADP reductase 2

1

5

High-throughput

0.407

High

147279

BIPA
Large ribosomal subunit assembly factor BipA

1

4

High-throughput

0.407

High

203638

YKPA
Uncharacterized ABC transporter ATP-binding protein YkpA

1

1

High-throughput

0.407

High

203647

SYP
Proline--tRNA ligase

1

1

High-throughput

0.407

High

203650

RNJ2
Ribonuclease J2

1

1

High-throughput

0.407

High

203728

SYDND
Aspartate--tRNA(Asp/Asn) ligase

1

2

High-throughput

0.407

High

203729

SYH
Histidine--tRNA ligase

1

1

High-throughput

0.407

High

203770

SUFB
Iron-sulfur cluster assembly protein SufB

1

1

High-throughput

0.407

High

203774

SUFD
Iron-sulfur cluster assembly protein SufD

1

1

High-throughput

0.407

High

203776

METN
Methionine import ATP-binding protein MetN

1

1

High-throughput

0.407

High

203818

LUTC
Lactate utilization protein C

1

1

High-throughput

0.407

High

203879

YCEE
Uncharacterized protein YceE

1

2

High-throughput

0.407

High

203880

GLTB
Glutamate synthase [NADPH] small chain

1

3

High-throughput

0.407

High

203951

YJOB
Uncharacterized ATPase YjoB

1

1

High-throughput

0.407

High

203995

BDHA
(R,R)-butanediol dehydrogenase

1

1

High-throughput

0.407

High

204016

GLMM
Phosphoglucosamine mutase

1

1

High-throughput

0.407

High

204032

UVRA
UvrABC system protein A

1

1

High-throughput

0.407

High

204047

YKWC
Uncharacterized oxidoreductase YkwC

1

1

High-throughput

0.407

High

361949

PUR1
Amidophosphoribosyltransferase

1

2

High-throughput

0.407

High

383026

RL7
Large ribosomal subunit protein bL12

1

1

High-throughput

0.407

High

420196

THRC
Threonine synthase

1

2

High-throughput

0.407

High

456477

FUMC
Fumarate hydratase class II

1

2

High-throughput

0.407

High

465311

SDHA
Succinate dehydrogenase flavoprotein subunit

1

1

High-throughput

0.407

High

470389

AK2
Aspartokinase 2

1

1

High-throughput

0.407

High

476451

PT1
Phosphoenolpyruvate-protein phosphotransferase

1

1

High-throughput

0.407

High

480481

ACNA
Aconitate hydratase A

1

1

High-throughput

0.407

High

509975

GLMS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

2

High-throughput

0.407

High

551645

PUR8
Adenylosuccinate lyase

1

2

High-throughput

0.407

High

578015

THIO
Thioredoxin

1

2

High-throughput

0.407

High

593880

KAD
Adenylate kinase

1

1

High-throughput

0.407

High

607821

HIS8
Histidinol-phosphate aminotransferase

1

1

High-throughput

0.407

High

608400

DNAK
Chaperone protein DnaK

1

4

High-throughput

0.407

High

609171

IF2
Translation initiation factor IF-2

1

4

High-throughput

0.407

High

613249

PGCA
Phosphoglucomutase

1

1

High-throughput

0.407

High

613281

CARY
Carbamoyl phosphate synthase arginine-specific large chain

1

1

High-throughput

0.407

High

635923

OBG
GTPase Obg

1

2

High-throughput

0.407

High

638568

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.407

High

662010

ARGC
N-acetyl-gamma-glutamyl-phosphate reductase

1

1

High-throughput

0.407

High

669449

PYRC
Dihydroorotase

1

1

High-throughput

0.407

High

669450

SRFAA
Surfactin synthase subunit 1

1

6

High-throughput

0.407

High

669458

EFTU
Elongation factor Tu

1

2

High-throughput

0.407

High

669459

SYL
Leucine--tRNA ligase

1

4

High-throughput

0.407

High

669463

SYM
Methionine--tRNA ligase

1

2

High-throughput

0.407

High

669465

SYK
Lysine--tRNA ligase

1

2

High-throughput

0.407

High

669467

YCHF
Ribosome-binding ATPase YchF

1

2

High-throughput

0.407

High

669470

CLPC
Negative regulator of genetic competence ClpC/MecB

1

1

High-throughput

0.407

High

669472

ATPA
ATP synthase subunit alpha

1

1

High-throughput

0.407

High

669473

ATPB
ATP synthase subunit beta

1

1

High-throughput

0.407

High

669479

LON1
Lon protease 1

1

1

High-throughput

0.407

High

669480

ILVA
L-threonine dehydratase biosynthetic IlvA

1

2

High-throughput

0.407

High

669481

RS1H
Small ribosomal subunit protein bS1 homolog

1

1

High-throughput

0.407

High

669482

DHBA
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

1

1

High-throughput

0.407

High

669486

DLTA
D-alanine--D-alanyl carrier protein ligase

1

6

High-throughput

0.407

High

669487

SYN
Asparagine--tRNA ligase

1

2

High-throughput

0.407

High

669489

CLPY
ATP-dependent protease ATPase subunit ClpY

1

2

High-throughput

0.407

High

669492

DHBE
2,3-dihydroxybenzoate-AMP ligase

1

5

High-throughput

0.407

High

669493

YXJG
Uncharacterized protein YxjG

1

2

High-throughput

0.407

High

669494

YXJH
Uncharacterized protein YxjH

1

2

High-throughput

0.407

High

669495

RL2
Large ribosomal subunit protein uL2

1

2

High-throughput

0.407

High

669497

DHNA
NADH dehydrogenase

1

4

High-throughput

0.407

High

669501

DHBF
Dimodular nonribosomal peptide synthase

1

6

High-throughput

0.407

High

669506

GUDB
Cryptic catabolic NAD-specific glutamate dehydrogenase GudB

1

1

High-throughput

0.407

High

669507

PNP
Polyribonucleotide nucleotidyltransferase

1

1

High-throughput

0.407

High

669509

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

1

3

High-throughput

0.407

High

669511

FABG
3-oxoacyl-[acyl-carrier-protein] reductase FabG

1

2

High-throughput

0.407

High

669514

BIOB
Biotin synthase

1

1

High-throughput

0.407

High

669519

ASNB
Asparagine synthetase [glutamine-hydrolyzing] 1

1

2

High-throughput

0.407

High

669522

DHLE
Leucine dehydrogenase

1

1

High-throughput

0.407

High

669524

FABI
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI

1

2

High-throughput

0.407

High

669530

FABL
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabL

1

1

High-throughput

0.407

High

669534

TIG
Trigger factor

1

1

High-throughput

0.407

High

669536

LEUC
3-isopropylmalate dehydratase large subunit

1

1

High-throughput

0.407

High

669537

6PGD
6-phosphogluconate dehydrogenase, NADP(+)-dependent, decarboxylating

1

1

High-throughput

0.407

High

669541

SUFC
Vegetative protein 296

1

1

High-throughput

0.407

High

669542

EFG
Elongation factor G

1

1

High-throughput

0.407

High

669543

G16U
General stress protein 16U

1

2

High-throughput

0.407

High

669544

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

2

High-throughput

0.407

High

669545

KPYK
Pyruvate kinase

1

1

High-throughput

0.407

High

669546

SCP2
Stress response protein SCP2

1

2

High-throughput

0.407

High

669551

MIND
Septum site-determining protein MinD

1

1

High-throughput

0.407

High

669553

SRFAB
Surfactin synthase subunit 2

1

6

High-throughput

0.407

High

669554

AK1
Aspartokinase 1

1

1

High-throughput

0.407

High

669555

DHAS
Aspartate-semialdehyde dehydrogenase

1

1

High-throughput

0.407

High

669560

SRFAC
Surfactin synthase subunit 3

1

6

High-throughput

0.407

High

669561

SYI
Isoleucine--tRNA ligase

1

3

High-throughput

0.407

High

669562

RNJ1
Ribonuclease J1

1

1

High-throughput

0.407

High

632025

RPOA
DNA-directed RNA polymerase subunit alpha

1

0

High-throughput

0.303

High

147082

YUGJ
Probable NADH-dependent butanol dehydrogenase 1

1

0

High-throughput

0.232

Low

147142

ALDH5
Benzaldehyde dehydrogenase YfmT

1

0

High-throughput

0.232

Low

147143

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A

1

0

High-throughput

0.232

Low

147199

LUTB
Lactate utilization protein B

1

0

High-throughput

0.232

Low

147273

LPLJ
Lipoate-protein ligase LplJ

1

0

High-throughput

0.232

Low

203472

GATB
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B

1

0

High-throughput

0.232

Low

203601

PEPF
Oligopeptidase PepF

1

0

High-throughput

0.232

Low

203614

THIG
Thiazole synthase

1

0

High-throughput

0.232

Low

203615

THIF
Sulfur carrier protein ThiS adenylyltransferase

1

0

High-throughput

0.232

Low

203616

METI
Cystathionine gamma-synthase/O-acetylhomoserine

1

0

High-throughput

0.232

Low

203627

MTNA
Methylthioribose-1-phosphate isomerase

1

0

High-throughput

0.232

Low

203628

MTNK
Methylthioribose kinase

1

0

High-throughput

0.232

Low

203629

MTNW
2,3-diketo-5-methylthiopentyl-1-phosphate enolase

1

0

High-throughput

0.232

Low

203630

MTND
Acireductone dioxygenase

1

0

High-throughput

0.232

Low

203632

YKVY
Putative dipeptidase YkvY

1

0

High-throughput

0.232

Low

203720

YOKG
SPbeta prophage-derived pesticidal crystal protein-like YokG

1

0

High-throughput

0.232

Low

203748

PNCB
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.232

Low

203773

SUFS
Cysteine desulfurase SufS

1

0

High-throughput

0.232

Low

203794

GR
Glyoxal reductase

1

0

High-throughput

0.232

Low

203799

CYSI
Sulfite reductase [NADPH] hemoprotein beta-component

1

0

High-throughput

0.232

Low

203875

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.232

Low

203901

YOPQ
SPbeta prophage-derived uncharacterized protein YopQ

1

0

High-throughput

0.232

Low

203918

6PGL
6-phosphogluconolactonase

1

0

High-throughput

0.232

Low

203934

PFKA
ATP-dependent 6-phosphofructokinase

1

0

High-throughput

0.232

Low

203938

CYSC1
Probable adenylyl-sulfate kinase

1

0

High-throughput

0.232

Low

203993

SAT1
Sulfate adenylyltransferase

1

0

High-throughput

0.232

Low

203996

YDJI
Uncharacterized protein YdjI

1

0

High-throughput

0.232

Low

204019

YCEH
Uncharacterized protein YceH

1

0

High-throughput

0.232

Low

204031

YOAC
Putative sugar kinase YoaC

1

0

High-throughput

0.232

Low

204041

DEOD
Purine nucleoside phosphorylase DeoD-type

1

0

High-throughput

0.232

Low

204049

MAO4
Bifunctional malic/malolactic enzyme

1

0

High-throughput

0.232

Low

204050

RL31B
Large ribosomal subunit protein bL31B

1

0

High-throughput

0.232

Low

204051

DAPH
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase

1

0

High-throughput

0.232

Low

394005

FLA
Flagellin

1

0

High-throughput

0.232

Low

420170

RS11
Small ribosomal subunit protein uS11

1

0

High-throughput

0.232

Low

432146

DPO3B
Beta sliding clamp

1

0

High-throughput

0.232

Low

432153

GYRA
DNA gyrase subunit A

1

0

High-throughput

0.232

Low

476423

DBH1
DNA-binding protein HU 1

1

0

High-throughput

0.232

Low

479294

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

0

High-throughput

0.232

Low

551642

PURL
Phosphoribosylformylglycinamidine synthase subunit PurL

1

0

High-throughput

0.232

Low

551643

PURE
N5-carboxyaminoimidazole ribonucleotide mutase

1

0

High-throughput

0.232

Low

551644

PUR7
Phosphoribosylaminoimidazole-succinocarboxamide synthase

1

0

High-throughput

0.232

Low

551647

PUR9
Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.232

Low

561075

ALF
Probable fructose-bisphosphate aldolase

1

0

High-throughput

0.232

Low

571047

KPRS
Ribose-phosphate pyrophosphokinase

1

0

High-throughput

0.232

Low

599673

RECA
Protein RecA

1

0

High-throughput

0.232

Low

605868

RIBBA
Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase

1

0

High-throughput

0.232

Low

608994

FTSZ
Cell division protein FtsZ

1

0

High-throughput

0.232

Low

609563

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.232

Low

613663

SYT1
Threonine--tRNA ligase 1

1

0

High-throughput

0.232

Low

615327

MURB
UDP-N-acetylenolpyruvoylglucosamine reductase

1

0

High-throughput

0.232

Low

624960

TAL
Transaldolase

1

0

High-throughput

0.232

Low

629556

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.232

Low

634298

AROA
3-phosphoshikimate 1-carboxyvinyltransferase

1

0

High-throughput

0.232

Low

638571

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.232

Low

638572

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.232

Low

641727

IMDH
Inosine-5'-monophosphate dehydrogenase

1

0

High-throughput

0.232

Low

641728

DLDH1
Dihydrolipoyl dehydrogenase

1

0

High-throughput

0.232

Low

641729

ODPA
Pyruvate dehydrogenase E1 component subunit alpha

1

0

High-throughput

0.232

Low

641730

ODPB
Pyruvate dehydrogenase E1 component subunit beta

1

0

High-throughput

0.232

Low

646975

SYE
Glutamate--tRNA ligase

1

0

High-throughput

0.232

Low

664536

PRSA
Foldase protein PrsA

1

0

High-throughput

0.232

Low

668507

TENA
Aminopyrimidine aminohydrolase

1

0

High-throughput

0.232

Low

669447

MNMG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

1

0

High-throughput

0.232

Low

669448

PYRF
Orotidine 5'-phosphate decarboxylase

1

0

High-throughput

0.232

Low

669451

SP5G
Putative septation protein SpoVG

1

0

High-throughput

0.232

Low

669452

SECA
Protein translocase subunit SecA

1

0

High-throughput

0.232

Low

669453

HPF
Ribosome hibernation promotion factor

1

0

High-throughput

0.232

Low

669454

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.232

Low

669455

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.232

Low

669456

AROC
Chorismate synthase

1

0

High-throughput

0.232

Low

669460

ARGJ
Arginine biosynthesis bifunctional protein ArgJ [Cleaved into: Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain] [Includes: Glutamate N-acetyltransferase

1

0

High-throughput

0.232

Low

669461

SRP54
Signal recognition particle protein

1

0

High-throughput

0.232

Low

669462

ILVC
Ketol-acid reductoisomerase

1

0

High-throughput

0.232

Low

669464

FTSH
ATP-dependent zinc metalloprotease FtsH

1

0

High-throughput

0.232

Low

669466

PPAC
Manganese-dependent inorganic pyrophosphatase

1

0

High-throughput

0.232

Low

669468

PDXS
Pyridoxal 5'-phosphate synthase subunit PdxS

1

0

High-throughput

0.232

Low

669469

PDXT
Pyridoxal 5'-phosphate synthase subunit PdxT

1

0

High-throughput

0.232

Low

669471

CHEV
Chemotaxis protein CheV

1

0

High-throughput

0.232

Low

669474

ENO
Enolase

1

0

High-throughput

0.232

Low

669475

RPOB
DNA-directed RNA polymerase subunit beta

1

0

High-throughput

0.232

Low

669476

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.232

Low

669477

ACKA
Acetate kinase

1

0

High-throughput

0.232

Low

669483

CISY2
Citrate synthase 2

1

0

High-throughput

0.232

Low

669484

IDH
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.232

Low

669485

GLYA
Serine hydroxymethyltransferase

1

0

High-throughput

0.232

Low

669488

GPMI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase

1

0

High-throughput

0.232

Low

669491

GLTA
Glutamate synthase [NADPH] large chain

1

0

High-throughput

0.232

Low

669496

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

669498

TKT
Transketolase

1

0

High-throughput

0.232

Low

669499

DHBB
Isochorismatase

1

0

High-throughput

0.232

Low

669500

DHBC
Isochorismate synthase DhbC

1

0

High-throughput

0.232

Low

669502

YQAP
Uncharacterized protein YqaP

1

0

High-throughput

0.232

Low

669503

SYR
Arginine--tRNA ligase

1

0

High-throughput

0.232

Low

669504

ACCC1
Biotin carboxylase 1

1

0

High-throughput

0.232

Low

669505

MDH
Malate dehydrogenase

1

0

High-throughput

0.232

Low

669510

ILVD
Dihydroxy-acid dehydratase

1

0

High-throughput

0.232

Low

669512

AAT1
Aspartate aminotransferase

1

0

High-throughput

0.232

Low

669513

BIOK
L-Lysine--8-amino-7-oxononanoate transaminase

1

0

High-throughput

0.232

Low

669515

SODM
Superoxide dismutase [Mn]

1

0

High-throughput

0.232

Low

669516

SYGB
Glycine--tRNA ligase beta subunit

1

0

High-throughput

0.232

Low

669517

FOLD
Bifunctional protein FolD [Includes: Methylenetetrahydrofolate dehydrogenase

1

0

High-throughput

0.232

Low

669518

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.232

Low

669520

YQEY
Uncharacterized protein YqeY

1

0

High-throughput

0.232

Low

669521

ISPG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

1

0

High-throughput

0.232

Low

669523

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.232

Low

669525

PSPA
Phage shock protein A homolog

1

0

High-throughput

0.232

Low

669526

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.232

Low

669527

IF3
Translation initiation factor IF-3

1

0

High-throughput

0.232

Low

669528

FABD
Malonyl CoA-acyl carrier protein transacylase

1

0

High-throughput

0.232

Low

669529

DIV4A
Septum site-determining protein DivIVA

1

0

High-throughput

0.232

Low

669531

SP0M
Sporulation-control protein spo0M

1

0

High-throughput

0.232

Low

669532

AHPC
Alkyl hydroperoxide reductase C

1

0

High-throughput

0.232

Low

669533

GREA
Transcription elongation factor GreA

1

0

High-throughput

0.232

Low

669535

EFTS
Elongation factor Ts

1

0

High-throughput

0.232

Low

669538

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.232

Low

669539

TPX
Thiol peroxidase

1

0

High-throughput

0.232

Low

669540

SUCD
Succinate--CoA ligase [ADP-forming] subunit alpha

1

0

High-throughput

0.232

Low

669547

RRF
Ribosome-recycling factor

1

0

High-throughput

0.232

Low

669548

GCH4
GTP cyclohydrolase FolE2

1

0

High-throughput

0.232

Low

669549

YCIC
Zinc chaperone YciC

1

0

High-throughput

0.232

Low

669550

CSHA
DEAD-box ATP-dependent RNA helicase CshA

1

0

High-throughput

0.232

Low

669552

MURE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase

1

0

High-throughput

0.232

Low

669556

GTAB
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.232

Low

669557

SYC
Cysteine--tRNA ligase

1

0

High-throughput

0.232

Low

669558

RL1
Large ribosomal subunit protein uL1

1

0

High-throughput

0.232

Low

669559

WAPI
Immunity protein WapI

1

0

High-throughput

0.232

Low

669563

NADA
Quinolinate synthase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025